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Name Synonyms FDA Status Company Target Type Therapy Type Approved
For
Atorvastatin Lipitor™ ,
Zarator®,
Sortis®,
Tahor®
Alzheimer's Disease (Inactive) Pfizer Cholesterol Small Molecule Hypercholesterolaemia
CS6253 Cogpep™,
CS-6253
Alzheimer's Disease (Phase 1) Artery Therapeutics, Inc. Amyloid-Related, Cholesterol Small Molecule
Efavirenz Efavirenz Alzheimer's Disease (Phase 1) Amyloid-Related, Tau, Cholesterol Small Molecule HIV infection
Gemfibrozil Lopid,
Jezil,
Gen-Fibro
Alzheimer's Disease (Phase 1) Cholesterol Small Molecule Hyperlipidemia
GSK2647544 GSK-2647544 Alzheimer's Disease (Phase 1) GlaxoSmithKline (GSK) Cholesterol Small Molecule
Obicetrapib TA-8995 Alzheimer's Disease (Phase 2) NewAmsterdam Pharma Cholesterol Small Molecule
Simvastatin Zocor®,
Lipex®,
Lipovas®,
Denan®
Alzheimer's Disease (Inactive), Mild Cognitive Impairment (Phase 4) Merck Cholesterol Small Molecule Hypercholesterolemia and diabetic cardiomyopathy.
Trappsol® Cyclo™ HP-beta-CD,
HPbetaCD
Alzheimer's Disease (Phase 2) Cyclo Therapeutics, Inc. Cholesterol Other