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Name | Synonyms | FDA Status | Company | Target Type | Therapy Type | Approved For |
---|---|---|---|---|---|---|
BIIB076 | NI-105, 6C5 huIgG1/l |
Alzheimer's Disease (Discontinued) | Biogen, Eisai Co., Ltd., Neurimmune | Tau | Immunotherapy (passive) | |
Davunetide | NAP, AL-108 |
Mild Cognitive Impairment (Discontinued), Progressive Supranuclear Palsy (Discontinued), Schizophrenia (Discontinued), Frontotemporal Dementia (Inactive) | Allon Therapeutics Inc., Paladin Labs Inc. | Tau | Other | |
Epothilone D | BMS-241027 | Alzheimer's Disease (Discontinued) | Bristol-Myers Squibb | Tau | Small Molecule | |
Gosuranemab | BIIB092, BMS-986168, IPN007 |
Progressive Supranuclear Palsy (Discontinued), Alzheimer's Disease (Discontinued) | Biogen, Bristol-Myers Squibb | Tau | Immunotherapy (passive) | |
Rember TM | Methylene Blue , methylthioninium (MT), TRx-0014, Tau aggregation inhibitor (TAI) |
Alzheimer's Disease (Discontinued) | TauRx Therapeutics Ltd | Tau | Small Molecule | Methylene Blue predates FDA. Used for treatment of malaria and methemoglobinemia. |
RG7345 | RO6926496 | Alzheimer's Disease (Discontinued) | Tau | Immunotherapy (passive) | ||
Tideglusib | NP031112, Nypta® , Zentylor™ , Glycogen synthase kinase 3 inhibitor, NP12 |
Alzheimer's Disease (Discontinued), Progressive Supranuclear Palsy (Discontinued) | Zeltia Group | Tau | Small Molecule | |
Tilavonemab | ABBV-8E12, C2N 8E12, HJ8.5 |
Progressive Supranuclear Palsy (Discontinued), Alzheimer's Disease (Discontinued) | AbbVie, C2N Diagnostics, LLC | Tau | Immunotherapy (passive) | |
Zagotenemab | LY3303560 | Alzheimer's Disease (Discontinued) | Eli Lilly & Co. | Tau, Unknown | Immunotherapy (passive) |