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Name Synonyms FDA Status Company Target Type Therapy Type Approved
For
AAV2-BDNF MCI due to AD (Phase 1), Alzheimer's Disease (Phase 1) Other DNA/RNA-based
ABBV-552 Alzheimer's Disease (Phase 1) AbbVie Other Small Molecule
ACD856 Alzheimer's Disease (Phase 1) AlzeCure Pharma AB Other Small Molecule
AL101 GSK-4527226 Alzheimer's Disease (Phase 1) Alector Other Immunotherapy (passive)
BIIB118 PF-05251749 Alzheimer's Disease (Phase 1), Parkinson's Disease (Phase 1) Biogen Other Small Molecule
Empagliflozin Jardiance,
BI-10773
Alzheimer's Disease (Phase 1) Boehringer Ingelheim, Eli Lilly & Co. Other Small Molecule Type 2 Diabetes, Cardiovascular disease
Emtricitabine Alzheimer's Disease (Phase 1) Gilead Sciences, Inc. Other Small Molecule
Focused Ultrasound – Blood-Brain Barrier FUS-BBB,
MRgFUS,
MRI-Guided Focused Ultrasound,
FUS+MB
Alzheimer's Disease (Phase 1), Amyotrophic Lateral Sclerosis (Phase 1), Mild Cognitive Impairment (Phase 1), Parkinson's Disease (Phase 1) Amyloid-Related, Other Procedural Intervention
IBC-Ab002 Alzheimer's Disease (Phase 1) ImmunoBrain Checkpoint Amyloid-Related, Inflammation, Other Immunotherapy (passive)
MemorEM Transcranial Electromagnetic Treatment TEMT Alzheimer's Disease (Phase 1) NeuroEM Therapeutics, Inc. Amyloid-Related, Other Procedural Intervention
NTRX-07 MDA7 Alzheimer's Disease (Phase 1) NeuroTherapia, Inc. Inflammation, Other Small Molecule
S-Equol Aus-131 Alzheimer's Disease (Phase 1) Ausio Pharmaceuticals, LLC Other Small Molecule