Martin Ingelsson on Alpha-synuclein gene rearrangements in dominantly inherited parkinsonism: frequency, phenotype, and mechanisms.
COMMENT It has been a good 10 years since the first disease-causing mutation in the α-synuclein gene (SNCA) was described in a family with autosomal-dominant Parkinson disease. However, in spite of a decade of intense research, only three pathogenic SNCA mutation