Alexei Koudinov on Immune hyporesponsiveness to amyloid beta-peptide in amyloid precursor protein transgenic mice: implications for the pathogenesis and treatment of Alzheimer's disease.

COMMENT Please see the following comments related to this article: Alzheimer’s anti-amyloid vaccination

Alexei Koudinov on The levels of soluble amyloid beta in different high density lipoprotein subfractions distinguish Alzheimer's and normal aging cerebrospinal fluid: implication for brain cholesterol pathology?

COMMENT Please do not miss our other contribution on this subject, especially: "Brain Cholesterol Pathology is the cause of Alzheimer's disease" Koudinov and Koudinova Clin Med Health Res,> Published November 27, 2002 [Full Text] see also: Alzhe

Alexei Koudinov on Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease.

COMMENT Please see the following letter in BMJ and Science related to this and previous article of DeMattos et al: Alzheimer’s anti-amyloid vaccination and statins: two approaches, one dogma. The time for change. Koudinov and Koudinova BMJ 20 March 2002 [Full Tex

Alexei Koudinov on Chronic nicotine treatment reduces beta-amyloidosis in the brain of a mouse model of Alzheimer's disease (APPsw).

COMMENT Please see the following letter in Science related to this article subject: Alzheimer’s anti-amyloid vaccination and statins: two approaches, one dogma. The time for change. Koudinov and Koudinova BMJ 20 March 2002 [Full Text] 0 postmaster

Alexei Koudinov on Nordihydroguaiaretic acid potently breaks down pre-formed Alzheimer's beta-amyloid fibrils in vitro.

COMMENT Please see the following comments related to this article: Alzheimer's disease and amyloid

Alexei Koudinov on Platelets in atherosclerosis: a new role for beta-amyloid peptide beyond Alzheimer's disease.

COMMENT Please see the following commentary related to this article: Alzheimer's disease and amyloid beta protein Koudinov AR et al Science online, Published 25 June 2002 [Full Text] 0 postmaster

Alexei Koudinov on Essential role for cholesterol in synaptic plasticity and neuronal degeneration.

COMMENT Please see postpublication of this report in Science: Cholesterol's role in synapse formation. Science 2002. 0 postmaster Cholesterol's role in synapse formation.

Alexei Koudinov on CNS synaptogenesis promoted by glia-derived cholesterol.

COMMENT Please see the following comment ont this article and its accompanying commentary:

Alexei Koudinov on Immunotherapy with beta-amyloid for Alzheimer's disease: a new frontier.

COMMENT Please see the following comments related to this article: Alzheimer’s anti-amyloid vaccination

Alexei Koudinov on Clearing the brain's amyloid cobwebs.

COMMENT Please see the following BMJ letter commenting on this and other related article: Alzheimer’s

Alexei Koudinov on Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid beta-peptide.

COMMENT Please the following BMJ letters commenting on this article: Cholesterol, synaptic function and

Alexei Koudinov on Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo.

COMMENT Please see the following letter published at British Medical Journal that comments on this

Alexei Koudinov on Predicting the failure of amyloid-beta vaccine.

COMMENT I highly recommend this letter and the following Acta Neuropathologica, Science and British Medical Journal letters: Dangers of the amyloid-beta vaccination. Smith MA, Joseph JA, Atwood CS, Perry G. Acta Neuropathol (Berl) 2002 Jul 104(1) 110 [PubMed] Alz

Alexei Koudinov on Diagnosing the Early Stages of Alzheimer's

COMMENT This very interesting article presents important knowledge on how the apoE isoforms affect brain function, memory, and memory dysfunction. The functional aspect is a major plus, as it extends the simplistic consideration of seeing the role of apoE in Alzh

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