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Brigita Urbanc on Amyloid Deposits Not Always Toxic to Cells

COMMENT This paper reports on several important findings derived from a carefully designed study on the VEGFR2 protein. Unlike Aβ-protein or α-synuclein, VEGFR2 does not aggregate in vivo under normal or pathogenic conditions. However, VEGFR2 can be induced to ...

Brigita Urbanc on Affibodies—Putting the β in Aβ?

COMMENT Capturing Aβ Using Engineered Affinity Proteins Alzheimer disease (AD) is associated with the amyloid-β protein (Aβ) which assembles into toxic oligomers, protofibrils, and fibrils, and is the major component of amyloid plaques in the AD brain. ...

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