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Colin Masters on Copper to the Rescue in ALS Mice

COMMENT Overall, results in the CCS/SOD mice look very promising, and are consistent with other experimental data that support the concept that altering copper levels in the CNS might have some therapeutic benefits in specific conditions. This could also include ...

Colin Masters on PBT2 Takes a Dive in Phase 2 Alzheimer’s Trial

COMMENT The IMAGINE study conducted by Prana Biotechnology was a small (n=42) exploratory trial supported by a grant from the Alzheimer’s Drug Discovery Foundation to see if the novel 8-OH quinoline (PBT2) would have an effect on Aβ-amyloid burden as reported by ...

Colin Masters on As DIAN’s Scope Widens, Funding Narrows

COMMENT Sanjay Pimplikar is a regular commentator on Alzforum. In the current comments, I think the view promoted is too pessimistic. Although we are already in a dire predicament today because there are no effective therapies for AD, there is considerable hope ...

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