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Richard Bedlack on Large ALS GWAS Identifies Modifiers of Survival

COMMENT I have personally seen more than 2,000 patients with ALS in the past 16 years. I believe the variability in the disease holds important clues to figuring out how to slow, stop, or reverse it. This interesting paper suggests that variations in two genes, ...

Richard Bedlack on Unusual ALS Case Highlights Variable Onset

COMMENT In my opinion the major message here is that there is a good deal of heterogeneity in all forms of ALS, even in specific subtypes of familial ALS such as this. This includes variability in penetrance, age and site of onset, comorbidities (for example ...

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