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Holger Wille on Amyloid-β Fibril Structure Bares All

COMMENT Another example of what the "resolution revolution" in cryo EM is giving us. In combination with rapidly developing image-processing algorithms, the new direct electron detectors allow us to finally get high-resolution views of nearly all ...

Robert Tycko on Amyloid-β Fibril Structure Bares All

COMMENT This is an important paper, demonstrating that detailed molecular structural information about Aβ fibrils can be obtained from cryoEM. Other labs have attempted this in earlier publications, but with less success. The success of this work by Gremer et al. ...

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