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Loss of Tau Function Triggers Insulin Resistance in the Brain

RESEARCH NEWS 2017-06-29 Research News Much ado has been made of the neuronal damage inflicted by aggregates of tau, but what about the cost of losing normal tau protein to these proteopathic snarls? In the June 26 Journal of Experimental Medicine, researchers led by David Blum ...

PAPER Marciniak E, Leboucher A, Caron E, Ahmed T, Tailleux A, Dumont J, Issad T, Gerhardt E, Pagesy P, Vileno M, Bournonville C, Hamdane M, Bantubungi K, Lancel S, Demeyer D, Eddarkaoui S, Vallez E, Vieau D, Humez S, Faivre E, Grenier-Boley B, Outeiro TF, Staels B, Amouyel P, Balschun D, Buee L, Blum D

Tau deletion promotes brain insulin resistance.

J Exp Med. 2017 Jun 26; PubMed: 28652303

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