CONFERENCE COVERAGE 2017-08-22 Conference Coverage As researchers analyze data in longitudinal biomarker studies, they find that some previously estimated biomarker trajectories do not hold up. At the Alzheimer’s Association International Conference 2017, held July 16–20 in London, one ...
PAPER Mander BA, Winer JR, Walker MP
CONFERENCE 2017-10-26 00:00:00-2017-10-27 00:00:00 San Francisco, California 26 – 27 October 2017 CurePSP conducts an annual research symposium that brings together international investigators to hear about and discuss the latest advances in prime of life neurodegeneration including PSP, CBD, ...
PAPER Ju YE, Ooms SJ, Sutphen C, Macauley SL, Zangrilli MA, Jerome G, Fagan AM, Mignot E, Zempel JM, Claassen JA, Holtzman DM
PAPER Romero-Corral A, Caples SM, Lopez-Jimenez F, Somers VK20202954
Fajardo, Puerto Rico
Brigham and Women's HospitalBoston, United States
PAPER Zhou X, Paushter DH, Feng T, Sun Li, Reinheckel T, Hu F
Federal University of Rio de JaneiroRio de Janeiro, Brazil
Thomas Kukar, Christopher Holler on Granulins: The Missing Link between Progranulin and Lysosome Function?
COMMENT The paper from Xiaolai Zhou et al. in Fenhua Hu's lab further supports the hypothesis that intracellular progranulin is processed into mature granulins in the lysosomal pathway. They demonstrate that modulation of cathepsin expression or ...
PAPER Holler CJ, Taylor G, Deng Q, Kukar T
PAPER Chang MC, Srinivasan K, Friedman BA, Suto E, Modrusan Z, Lee WP, Kaminker JS, Hansen DV, Sheng M28778989
COMMENT Tau Packs Heat No doubt tau protein is the culprit in its namesake diseases—the tauopathies, which include Alzheimer’s disease. Among the longstanding head-scratching problems in tau pathobiology is how tau, one of the most soluble proteins known, ...
COMMENT This study has addressed a salient issue in human astrocyte biology. It nicely confirms and extends a previous study by the Barres Lab (Zhang et al., 2016), which characterized purified astrocytes from fetal through to adult stages. It chronicles the ...
PAPER Knowles RB, Sabry JH, Martone ME, Deerinck TJ, Ellisman MH, Bassell GJ, Kosik KS8987809
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