University of SzegedSzeged, Hungary
RESEARCH NEWS 2016-05-28 Research News New research bolsters the case that brain-derived microglia need TREM2 to essentially wall off amyloid plaques, but exactly how they do that remains up for debate. As reported in the May 18 Neuron, scientists led by Jaime Grutzendler at Yale ...
RESEARCH NEWS 2016-05-27 Research News For all that researchers know about Aβ, the peptide so strongly linked to Alzheimer’s disease, they have scant knowledge of its normal function in or out of the cell. A new paper strengthens the idea that Aβ helps fights infection as part of ...
PAPER Chu H, Pazgier M, Jung G, Nuccio SP, Castillo PA, de Jong MF, Winter MG, Winter SE, Wehkamp J, Shen B, Salzman NH, Underwood MA, Tsolis RM, Young GM, Lu W, Lehrer RI, Bäumler AJ, Bevins CL22722251
PAPER Kumar DK, Choi SH, Washicosky KJ, Eimer WA, Tucker S, Ghofrani J, Lefkowitz A, McColl G, Goldstein LE, Tanzi RE, Moir RD
Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer's disease.Sci Transl Med. 2016 May 25;8(340):340ra72. PubMed: 27225182
Chigago, United States
Keio University School of MedicineTokyo
PAPER Fukumori A, Steiner H
Substrate recruitment of γ-secretase and mechanism of clinical presenilin mutations revealed by photoaffinity mapping.EMBO J. 2016 May 23; PubMed: 27220847
PAPER Ríos JL, Onteniente M, Picazo D, Montesinos MC27224274
PAPER Chen CH, Khan A, Huang JT, Ulmschneider MB27224887
PAPER Aragones JM, Altimiras J, Roura-Poch P, Homs E, Bajo L, Povedano M, Cortés-Vicente E, Illa I, Al-Chalabi A, Rojas-García R27224687
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