COMMENT This is a very important paper, showing the unexpected result that semagacestat causes the accumulation of longer Aβ species and short peptide byproducts that are produced by the sequential carboxy-terminal trimming activity of γ-secretase. The paper ...
Bracket GlobalWayne, United States
KCL (Maurice Wohl Clinical Neuroscience Centre)London, United Kingdom
University of WI/MadisonMadison, United States
ADRx Inc.Thousand Oaks, United States
PAPER Bemiller SM, McCray TJ, Allan K, Formica SV, Xu G, Wilson G, Kokiko-Cochran ON, Crish SD, Lasagna-Reeves C, Ransohoff RM, Landreth GE, Lamb BT
JOB 2017-10-16 Employer Case Western Reserve University Contact Please submit CV, names and contact information for three references, and a description of your research experience to Dr. Safar, Jiri.Safar@case.edu. Description The laboratory of Dr. Jiri Safar in the ...
Ridgefield, United States
CWRUCleveland, United States
Kingfisher Talent, LLCCambridge, United States
Senior Living Dementia and Alzheimer's Greenville , United States
Roxana Carare, Roy Weller on Artificial Human Blood Vessels: A Model for Cerebral Amyloid Angiopathy?
COMMENT There is firm evidence from experimental studies and observations on human brains with Alzheimer’s disease that cerebral amyloid angiopathy is a consequence of a failure of clearance of Aβ and interstitial fluid from the brain. In order to test new ...
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