Virgil Muresan on Intraneuronal APP, not free Aβ peptides in 3xTg-AD mice: implications for tau versus Aβ-mediated Alzheimer neurodegeneration.
COMMENT We would like to comment on a few issues raised by this paper and previous comments, starting with the now old observations from various groups, Gunnar Gouras’s in particular (1), that in the AD brain Aβ accumulates in a population of neurons in the vulne