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J Chem Inf Model. 2011 Nov 22; PubMed: 22012737PAPER Darreh-Shori T, Siawesh M, Mousavi M, Andreasen N, Nordberg A
Apolipoprotein ε4 Modulates Phenotype of Butyrylcholinesterase in CSF of Patients with Alzheimer's Disease.
J Alzheimers Dis. 2011 Oct 19; PubMed: 22012848Elizabeth Gjoneska on Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans.
COMMENT What if the elixir of life is encoded in the epigenome and longevity is transmitted in a hereditary fashion? The study by Greer and colleagues certainly seems to indicate that this concept holds true, and provides the first example of transgenerational ep
Elizabeth Gjoneska
Picower Institute for Learning and Memory, MITCambridge, United States
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Epidemiological studies on asbestos-exposed workers in South Africa.
Hefte Unfallheilkd. 1975 Nov;(126):538-42. PubMed: 1234264PAPER Greer EL, Maures TJ, Ucar D, Hauswirth AG, Mancini E, Lim JP, Benayoun BA, Shi Y, Brunet A
Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans.
Nature. 2011 Nov 17;479(7373):365-71. PubMed: 22012258PAPER Ng SF, Lin RC, Laybutt DR, Barres R, Owens JA, Morris MJ
Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring.
Nature. 2010 Oct 21;467(7318):963-6. PubMed: 20962845PAPER Carone BR, Fauquier L, Habib N, Shea JM, Hart CE, Li R, Bock C, Li C, Gu H, Zamore PD, Meissner A, Weng Z, Hofmann HA, Friedman N, Rando OJ
Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals.
Cell. 2010 Dec 23;143(7):1084-96. PubMed: 21183072PAPER Greer EL, Maures TJ, Hauswirth AG, Green EM, Leeman DS, Maro GS, Han S, Banko MR, Gozani O, Brunet A
Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans.
Nature. 2010 Jul 15;466(7304):383-7. PubMed: 20555324PAPER Alonso M, Viollet C, Gabellec MM, Meas-Yedid V, Olivo-Marin JC, Lledo PM