PAPER Georgy GS, Nassar NN, Mansour HA, Abdallah DM
SEARCH RESULTS
330026 RESULTS
PAPER Bezprozvanny I
Presenilins and calcium signaling-systems biology to the rescue.
Sci Signal. 2013 Jul 9;6(283):pe24. PubMed: 23838181Jean Georges
Alzheimer EuropeUnited States
PAPER Miller R, Ito K, Lalovic B
Models for event-driven data: longitudinal daily adverse event and dropout.
J Clin Pharmacol. 2010 Sep;50(9 Suppl):58S-62S. PubMed: 20881219PAPER Romanelli MF, Morris JC, Ashkin K, Coben LA
Advanced Alzheimer's disease is a risk factor for late-onset seizures.
Arch Neurol. 1990 Aug;47(8):847-50. PubMed: 2375689TDP-43
ALZPEDIA In 2006, TAR DNA-binding protein 43 (TDP-43) was identified as the cardinal protein in the most common subtypes of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). Together with the 2006 discovery of progranulin, this was a major bre
TREM2
ALZPEDIA Triggering receptor expressed on myeloid cells 2 (TREM2) is a receptor of the innate immune system expressed on microglia, macrophages, dendritic cells, and osteoclasts. TREM2 is a member of the immunoglobulin superfamily. Endogenous ligands of this recep
PICALM
ALZPEDIA PICALM is an accessory protein in the endocytic pathway. Ubiquitously expressed, PICALM binds to clathrin and its adaptor proteins, which together regulate the formation of the clathrin lattice during endocytosis. PICALM was identified in one of the first
Complement Receptor 1 (CR1)
ALZPEDIA The complement receptor 1 (CR1) gene encodes a transmembrane glycoprotein that functions in the innate immune system. CR1 is expressed on blood cells and microglia. As a receptor for the complement components C3b and C4b, CR1 helps regulate activation of
Anouchka Seesaghur
Decision Resources Group
Clusterin
ALZPEDIA Clusterin is a highly conserved glycoprotein that functions primarily as an extracellular chaperone. Multiple large genome-wide association studies (GWAS) have uncovered clusterin variants that strongly associate with late-onset Alzheimer’s disease, earni
APOE
ALZPEDIA Apolipoprotein E is a secreted apolipoprotein involved in lipid metabolism. It complexes with lipids to form lipoprotein particles that transport cholesterol and triglycerides via the bloodstream and facilitate the transfer of cholesterol and phospholipid
Jean Georges on AD Trial Simulation Tool Receives Regulators’ Blessings
COMMENT The patient and carer community in Europe was disappointed by the failures of recent clinical trials in the field of Alzheimer’s disease. Alzheimer Europe therefore welcomes research into the development of simulation models for clinical trials that hopef
PAPER Rajput A, Rajput AH, Rajput ML, Encarnacion M, Bernales CQ, Ross JP, Farrer MJ, Vilariño-Güell C
Identification of FUS p.R377W in essential tremor.
Eur J Neurol. 2013 Jul 3; PubMed: 23834483PAPER Nishimoto Y, Nakagawa S, Hirose T, Okano HJ, Takao M, Shibata S, Suyama S, Kuwako K, Imai T, Murayama S, Suzuki N, Okano H
The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis.
Mol Brain. 2013;6:31. PubMed: 23835137Current Filters
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