PAPER Gregory RI, Yan KP, Amuthan G, Chendrimada T, Doratotaj B, Cooch N, Shiekhattar R
SEARCH RESULTS
330889 RESULTS
PAPER Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G
Numerous microRNPs in neuronal cells containing novel microRNAs.
RNA. 2003 Feb;9(2):180-6. PubMed: 12554860Michael Wolfe on Three-amino acid spacing of presenilin endoproteolysis suggests a general stepwise cleavage of gamma-secretase-mediated intramembrane proteolysis.
COMMENT This is a solid study that provides important confirmation that presenilin is a zymogen that cuts itself (i.e., it is its own “presenilinase”) and that autoproteolysis occurs stepwise, every ~3 amino acids, similar to what is seen with γ-secretase substra
Paul Coleman on Law and Disorder—APPswe Patent Suits Raise Ruckus Again
COMMENT I read this news story with sadness. I regret the lack of investigators cooperating on the basis of mutual trust and a handshake. Of course, that is still possible among some, but these days commercial/monetary/legal issues are too often inserted to the d
Motor Neuron Disease Risk Factors: Fresh miRNA Clue, KIFAP3 Letdown
RESEARCH NEWS 2010-06-29 Research News Sifting through the genome has netted several mutations responsible for motor neuron diseases, but scientists still cannot explain the cause for most incidences. For amyotrophic lateral sclerosis (ALS), an adult-onset condition, genetics exp
AβPP
ANTIBODY polyclonal manufacturer Cat# LS-B3672<br /> manufacturer: LifeSpan Biosciences immunogen = peptide corresp. to aa737-751 of human amyloid A4 protein precursor (APP) or residues 85-99 of the C99 fragment generated by β- and γ-secretases. liquid, PBS,
AβPP
ANTIBODY polyclonal manufacturer Cat# LS-B3671<br /> manufacturer: LifeSpan Biosciences immunogen = peptide corresp. to aa653-662 of human amyloid A4 protein precursor (APP) or aa1-10 of the 4K Ab peptide generated by β- and γ-secretases. liquid, PBS, azide,
AβPP (J4H9)
ANTIBODY monoclonal J4H9 manufacturer Cat# LS-B2970<br /> manufacturer: LifeSpan Biosciences immunogen = APP antibody was raised against recombinant human APP (18-289aa) purified from E. coli liquid, PBS, azide APP IgG<sub>2b</sub>, κ APP, APLP,
APPβP2
ANTIBODY polyclonal manufacturer Cat# LS-C81701<br /> manufacturer: LifeSpan Biosciences immunogen = synthetic peptide corresp. to a region of human APPBP2 lyophilized, PBS, sucrose, affinity purified Amyloid Beta Precursor Protein (cytoplasmic Tail)-binding
APβA3
ANTIBODY polyclonal manufacturer Cat# LS-C102837<br /> manufacturer: LifeSpan Biosciences immunogen = synthetic peptide corresp. to a region of human APBA3 lyophilized, PBS, sucrose, affinity purified amyloid beta (A4) precursor protein-binding, family A, me
AβPP
ANTIBODY polyclonal manufacturer Cat# LS-C20540<br /> manufacturer: LifeSpan Biosciences immunogen = synthetic peptide of Amyloid-Beta protein 1-40 liquid, unpurified serum, azide recognizes Amyloid-β protein 1-40 (βAP), but not with either βAP 17-42 or secr
AβPP
ANTIBODY polyclonal manufacturer Cat# LS-C101427<br /> manufacturer: LifeSpan Biosciences immunogen = synthetic peptide corresp. to a region of human APP lyophilized, PBS, azide, sucrose, affinity purified APP IgG APP, APLP, AICD Autogen Bioclear Rabbit Huma
AβPP
ANTIBODY polyclonal manufacturer Cat# LS-C3658<br /> manufacturer: LifeSpan Biosciences immunogen = synthetic peptide that corresponds to a part of KPI domain in soluble APP liquid, unpurified serum, azide, glycerol recognizes soluble APP and synthetic pepti
AβPP (1B11F3)
ANTIBODY monoclonal 1B11F3 manufacturer Cat# LS-C47167 immunogen = Ni-NTA purified truncated recombinant APP expressed in E. coli strain BL21 (DE3) liquid, affinity purified rhAβPP IgG<sub>2a</sub> APP, APLP, AICD Autogen Bioclear Mouse Human A^
PAPER Jiang H, Wu YC, Nakamura M, Liang Y, Tanaka Y, Holmes S, Dawson VL, Dawson TM, Ross CA, Smith WW
Parkinson's disease genetic mutations increase cell susceptibility to stress: mutant alpha-synuclein enhances H2O2- and Sin-1-induced cell death.
Neurobiol Aging. 2007 Nov;28(11):1709-17. PubMed: 16978743Current Filters
No filters selected