PAPER Toro P, Degen C, Pierer M, Gustafson D, Schröder J, Schönknecht P
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330919 RESULTS
PAPER Scherling CS, Hall T, Berisha F, Klepac K, Karydas A, Coppola G, Kramer JH, Rabinovici G, Ahlijanian M, Miller BL, Seeley W, Grinberg LT, Rosen H, Meredith J Jr, Boxer AL
Cerebrospinal fluid neurofilament concentration reflects disease severity in frontotemporal degeneration.
Ann Neurol. 2014 Jan;75(1):116-26. Epub 2014 Jan 2 PubMed: 24242746PAPER Alcalay RN, Mirelman A, Saunders-Pullman R, Tang MX, Mejia Santana H, Raymond D, Roos E, Orbe-Reilly M, Gurevich T, Bar Shira A, Gana Weisz M, Yasinovsky K, Zalis M, Thaler A, Deik A, Barrett MJ, Cabassa J, Groves M, Hunt AL, Lubarr N, San Luciano M, Miravite J, Palmese C, Sachdev R, Sarva H, Severt L, Shanker V, Swan MC, Soto-Valencia J, Johannes B, Ortega R, Fahn S, Cote L, Waters C, Mazzoni P, Ford B, Louis E, Levy O, Rosado L, Ruiz D, Dorovski T, Pauciulo M, Nichols W, Orr-Urtreger A, Ozelius L, Clark L, Giladi N, Bressman S, Marder KS
Parkinson disease phenotype in Ashkenazi Jews with and without LRRK2 G2019S mutations.
Mov Disord. 2013 Dec;28(14):1966-71. Epub 2013 Oct 15 PubMed: 24243757PAPER Poojari C, Strodel B
Stability of transmembrane amyloid β-peptide and membrane integrity tested by molecular modeling of site-specific Aβ42 mutations.
PLoS One. 2013;8(11):e78399. Epub 2013 Nov 7 PubMed: 24244308PAPER Sanphui P, Pramanik SK, Chatterjee N, Moorthi P, Banerji B, Biswas SC
Efficacy of cyclin dependent kinase 4 inhibitors as potent neuroprotective agents against insults relevant to Alzheimer's disease.
PLoS One. 2013;8(11):e78842. Epub 2013 Nov 11 PubMed: 24244372PAPER Mengel-From J, Thinggaard M, Lindahl-Jacobsen R, McGue M, Christensen K, Christiansen L
CLU genetic variants and cognitive decline among elderly and oldest old.
PLoS One. 2013;8(11):e79105. Epub 2013 Nov 14 PubMed: 24244428PAPER Iascone DM, Padidam S, Pyfer MS, Zhang X, Zhao L, Chin J
Impairments in neurogenesis are not tightly linked to depressive behavior in a transgenic mouse model of Alzheimer's disease.
PLoS One. 2013;8(11):e79651. Epub 2013 Nov 14 PubMed: 24244537PAPER Ridge PG, Mukherjee S, Crane PK, Kauwe JS, Alzheimer’s Disease Genetics Consortium
Alzheimer's disease: analyzing the missing heritability.
PLoS One. 2013;8(11):e79771. Epub 2013 Nov 7 PubMed: 24244562PAPER Ding F, Yao J, Rettberg JR, Chen S, Brinton RD
Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention.
PLoS One. 2013;8(11):e79977. Epub 2013 Nov 11 PubMed: 24244584PAPER Vignaud H, Bobo C, Lascu I, Sörgjerd KM, Zako T, Maeda M, Salin B, Lecomte S, Cullin C
A structure-toxicity study of Aß42 reveals a new anti-parallel aggregation pathway.
PLoS One. 2013;8(11):e80262. Epub 2013 Nov 11 PubMed: 24244667PAPER Kandimalla RJ, Prabhakar S, Wani WY, Kaushal A, Gupta N, Sharma DR, Grover VK, Bhardwaj N, Jain K, Gill KD
CSF p-Tau levels in the prediction of Alzheimer's disease.
Biol Open. 2013;2(11):1119-24. Epub 2013 Sep 4 PubMed: 24244848APP(V642I)KI
RESEARCH MODELS Modification Details Targeted knock-in of the V642I mutation into exon 17 of the mouse APP gene using homologous recombination and the Cre-loxP system. Neuropathology Increased Aβ42(43) relative to Aβ40 at 29 months, but without neuritic plaques, neurofib
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