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Frontotemporal Dementia: The Hard Work of Pushing Toward Trials

CONFERENCE COVERAGE 2016-09-23 Conference Coverage In the last 10 years, the science of frontotemporal dementias has exploded, thanks to big openings in the molecular pathologies behind these disorders. Rapidly growing interest among academia and industry was on display at the 10th ...

Keith Vossel on Singling Out Aβ Assemblies: Focus on Trimers

COMMENT This is an important advance that builds on our understanding of key contributors to Aβ-induced deficits in axonal transport. Sherman et al. have created unique models in which to assess for Aβ and tau pathological interactions. They demonstrated that ...

Tau Deepens Cognitive Trouble in Lewy Body Diseases

RESEARCH NEWS 2016-09-23 Research News Clumps of α-synuclein in neurons define Lewy body diseases, but tau tangles may add their own stamp to these disorders. Results from an imaging study, published September 19 in JAMA Neurology, suggest that tau pathology packs a cognitive ...

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