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Chicago: 2nd Annual Symposium Explores ApoE

CONFERENCE COVERAGE 2011-07-26 Conference Coverage Download a PDF of this report. Apolipoprotein E (ApoE) gene alleles are the strongest genetic modulators of late-onset Alzheimer's disease (AD) risk. Some 60 percent of AD individuals carry at least one copy of the ApoE4 variant.

Editing Stem Cell DNA to Make the Perfect Cells for Study, Therapy

RESEARCH NEWS 2011-07-26 Research News Now that they can make induced pluripotent stem cells from anyone, scientists are near-giddy with excitement over the potential to model diseases in cell lines, as well as someday correct genetic mutations in people (see ARF news series). Bu

Sorting Out Parkinson’s: Exome Sequencing Points to Recycling Defect

RESEARCH NEWS 2011-07-26 Research News Sifting through the sequence of all the coding bits of the genome, two independent groups have identified a new mutation that causes Parkinson’s disease. The mutation sits in the gene for vacuolar protein sorting 35 (VPS35), altering its par

Slow Aβ; Clearance Is ApoE4’s Modus Operandi in Late-Onset AD

WEBINAR 2011-07-26 Alzforum has been pleased to partner with the journal Science Translational Medicine in hosting a Webinar discussion of a new Alzheimer’s disease research study published 29 June 2011. The journal generously granted free access to Castellano et al. for Al

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