PAPER Bihaqi SW, Zawia NH

Enhanced taupathy and AD-like pathology in aged primate brains decades after infantile exposure to lead (Pb).

Neurotoxicology. 2013 Aug 21;39C:95-101. PubMed: 23973560

PAPER Yamreudeewong W Pharmd Bcps Cacp, Teixeira MG Phd, Mayer GE Phd

Stability of Memantine in an Extemporaneously Prepared Oral Liquid.

Int J Pharm Compd. 2006 July-Aug;10(4):316-317. PubMed: 23974265

PAPER Ribeiro Morais G, Gano L, Kniess T, Bergmann R, Abrunhosa A, Santos I, Paulo A

Radiosynthesis and in vivo evaluation of a (18)F-labelled styryl-benzoxazole derivative for β-amyloid targeting.

Appl Radiat Isot. 2013 Dec;82:100-4. PubMed: 23974304

PAPER McLaughlin PM, Anderson ND, Rich JB, Chertkow H, Murtha SJ

Visual Selective Attention in Amnestic Mild Cognitive Impairment.

J Gerontol B Psychol Sci Soc Sci. 2013 Aug 23; PubMed: 23974434

PAPER Gräske J, Verbeek H, Gellert P, Fischer T, Kuhlmey A, Wolf-Ostermann K

How to measure quality of life in shared-housing arrangements? A comparison of dementia-specific instruments.

Qual Life Res. 2013 Aug 22; PubMed: 23975378

PAPER Okada H, Ouchi Y, Ogawa M, Futatsubashi M, Saito Y, Yoshikawa E, Terada T, Oboshi Y, Tsukada H, Ueki T, Watanabe M, Yamashita T, Magata Y

Alterations in α4β2 nicotinic receptors in cognitive decline in Alzheimer's aetiopathology.

Brain. 2013 Oct;136(Pt 10):3004-17. PubMed: 23975517

PAPER Zhang J, Wang C, Deng T, Xue Z, Chen X, Chang L, Wang Q

The preventive effect of NR2B and NR2D-containing NMDAR antagonists on Aβ-induced LTP disruption in the dentate gyrus of rats.

Metab Brain Dis. 2013 Dec;28(4):697-704. PubMed: 23975536

PAPER Deleglise B, Lassus B, Soubeyre V, Alleaume-Butaux A, Hjorth JJ, Vignes M, Schneider B, Brugg B, Viovy JL, Peyrin JM

Synapto-protective drugs evaluation in reconstructed neuronal network.

PLoS One. 2013;8(8):e71103. PubMed: 23976987

PAPER Zhang SQ, Sawmiller D, Li S, Rezai-Zadeh K, Hou H, Zhou S, Shytle D, Giunta B, Fernandez F, Mori T, Tan J

Octyl Gallate Markedly Promotes Anti-Amyloidogenic Processing of APP through Estrogen Receptor-Mediated ADAM10 Activation.

PLoS One. 2013;8(8):e71913. PubMed: 23977176

PAPER Honarmand Ebrahimi K, Dienemann C, Hoefgen S, Than ME, Hagedoorn PL, Hagen WR

The Amyloid Precursor Protein (APP) Does Not Have a Ferroxidase Site in Its E2 Domain.

PLoS One. 2013;8(8):e72177. PubMed: 23977245

PAPER Theunis C, Crespo-Biel N, Gafner V, Pihlgren M, López-Deber MP, Reis P, Hickman DT, Adolfsson O, Chuard N, Ndao DM, Borghgraef P, Devijver H, Van Leuven F, Pfeifer A, Muhs A

Efficacy and Safety of A Liposome-Based Vaccine against Protein Tau, Assessed in Tau.P301L Mice That Model Tauopathy.

PLoS One. 2013;8(8):e72301. PubMed: 23977276

PAPER Hsiao JH, Fu Y, Hill AF, Halliday GM, Kim WS

Elevation in sphingomyelin synthase activity is associated with increases in amyloid-Beta Peptide generation.

PLoS One. 2013;8(8):e74016. PubMed: 23977395

Lauren Friedman

United States

BACE1 Knock-out

RESEARCH MODELS Summary These mice have a targeted deletion in the mouse gene β-site APP cleaving enzyme 1 (BACE1). Homozygous mice are viable, fertile, normal in size, and do not display any gross physical or behavioral abnormalities. No BACE1 protein is detected by Wes

BACE2 Knock-out

RESEARCH MODELS Summary These mice have a targeted deletion of part of the mouse β-site APP-cleaving enzyme 2 (BACE2) gene. In contrast to animals with targeted deletion of BACE1, homozygous BACE2 null animals are viable, fertile, normal in size and do not display any gr