PAPER Montlahuc C, Soumaré A, Dufouil C, Berr C, Dartigues JF, Poncet M, Tzourio C, Alpérovitch A
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PAPER Selemon LD, Rajkowska G, Goldman-Rakic PS
Evidence for progression in frontal cortical pathology in late-stage Huntington's disease.
J Comp Neurol. 2004 Jan 6;468(2):190-204. PubMed: 14648679Martijn Gebbink
Crossbeta BiosciencesUtrecht, Netherlands
Armand Tepper
Crossbeta BiosciencesUtrecht, Netherlands
PAPER Stacher G, Bauer P, Brunner H, Grünberger J
Gastric acid secretion, serum-gastrin levels and psychomotor function under the influence of placebo, insulin-hypoglycemia, and/or bromazepam.
Int J Clin Pharmacol Biopharm. 1976 Jan;13(1):1-10. PubMed: 2560PAPER Mraz W, Fischer G, Jatzkewitz H
The activator of human cerebroside sulphatase. Activating effect on the acidic forms of the sulphatases from invertebrates.
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CONFERENCE COVERAGE 2011-10-13 Conference Coverage This meeting could not avoid a discussion of semagacestat/LY450139, a γ-secretase inhibitor whose development ended in 2010 following cognitive worsening and other side effects in Phase 3. The pharmacology of semagacestat included a re
Tracking Huntington’s: Could Histone Protein Hit The Mark?
RESEARCH NEWS 2011-10-13 Research News In the quest for a Huntington’s disease biomarker—one that reliably tracks disease progress and therapeutic response—researchers have so far come up short. Behavioral tests, neuroimages, and cerebrospinal fluid markers, which are panning out
Could Asking People How They Feel Help Predict Dementia?
RESEARCH NEWS 2011-10-13 Research News Imaging the living brain, searching for telltale molecules in the cerebrospinal fluid, and measuring memory and thinking skills—these are among the tests scientists use to figure out who might eventually develop Alzheimer’s disease (AD). But
PAPER Kazui H, Takeda M
[Language impairment and semantic memory loss of semantic dementia].
Brain Nerve. 2011 Oct;63(10):1047-55. PubMed: 21987562PAPER Saleh A, Smith DR, Balakrishnan S, Dunn L, Martens C, Tweed CW, Fernyhough P
Tumor necrosis factor-α elevates neurite outgrowth through an NF-κB-dependent pathway in cultured adult sensory neurons: Diminished expression in diabetes may contribute to sensory neuropathy.
Brain Res. 2011 Nov 14;1423:87-95. PubMed: 21985959PAPER Salter MW, Pitcher GM
Dysregulated Src upregulation of NMDA receptor activity: a common link in chronic pain and schizophrenia.
FEBS J. 2012 Jan;279(1):2-11. PubMed: 21985289PAPER Keryer G, Pineda JR, Liot G, Kim J, Dietrich P, Benstaali C, Smith K, Cordelières FP, Spassky N, Ferrante RJ, Dragatsis I, Saudou F
Ciliogenesis is regulated by a huntingtin-HAP1-PCM1 pathway and is altered in Huntington disease.
J Clin Invest. 2011 Nov 1;121(11):4372-82. PubMed: 21985783PAPER Quintanar L, Montiel T, Márquez M, González A, Massieu L
Calpain activation is involved in acute manganese neurotoxicity in the rat striatum in vivo.
Exp Neurol. 2011 Oct 1; PubMed: 21985864PAPER Jia X, Gharibyan AL, Öhman A, Liu Y, Olofsson A, Morozova-Roche LA
Neuroprotective and nootropic drug noopept rescues α-synuclein amyloid cytotoxicity.
J Mol Biol. 2011 Dec 16;414(5):699-712. PubMed: 21986202Current Filters
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