205115 RESULTS

Probe Shines a Light on γ-Secretase Inhibitor’s Broad Reach

RESEARCH NEWS 2017-01-14 Research News Efforts to derail the production of Aβ42 by targeting the enzyme that produces it, γ-secretase, have been complicated by the secretase’s complexity and promiscuity for substrates. In a paper published in Cell Chemical Biology on January 5, ...

NINDS Exploratory Clinical Trials (R01)

GRANT Friday, January 13, 2017- 16:15 National Institute of Neurological Disorders and Stroke March 21, 2017, then Standard dates apply, by 5 p.m. local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity ...

Forming FUS Droplets with a Flash of Light

RESEARCH NEWS 2017-01-13 Research News FUS, HNRNPA1, and other RNA-binding proteins implicated in ALS and other neurodegenerative diseases have a floppy tail. These intrinsically disordered regions (IDRs) allow proteins to undergo liquid phase separation and form liquid droplets. ...

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