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International Symposium on Recent Advances in Drug Delivery Systems 2005

CONFERENCE 2005-02-21 00:00:00-2005-02-24 00:00:00 Grand America Hotel, Salt Lake City, UT, U.S.A. 21 &#x2013 24 February 2005 The intent of this symposium is to bring together multidisciplinary researchers in the areas of pharmaceutics, polymer science, cell and molecular biology and medicine. The to

AAAS 2005 Annual Meeting

CONFERENCE 2005-02-17 00:00:00-2005-02-21 00:00:00 Washington, DC, U.S.A. 17 &#x2013 21 February 2005 2005 Annual Meeting Focusing on "The Nexus: Where Science Meets Society" Some 17 tentative session tracks were proposed by the AAAS Program Committee, with topics ranging from emerging disea

Cytokines, Disease and Therapeutic Intervention (B4)

CONFERENCE 2005-02-12 00:00:00-2005-02-17 00:00:00 Eldorado Hotel, Santa Fe, NM, U.S.A. 12 &#x2013 17 February 2005 With the completion of the human genome project, we will shortly know all of the cytokines encoded within our genome. Indeed within the last few years, there have been reports of at leas

NY Academy of Sciences Neuroimmunology Discussion

CONFERENCE 2005-02-02 00:00:00-2005-02-02 00:00:00 New York Academy of Sciences, New York, NY, U.S.A. 02 February 2005 The NY Academy of Sciences Neuroimmunology Discussion group invites you to participate in a poster session at its next meeting on February 2, 2005. Topic: Microglia: How They Function in

Dendritic Cells at the Center of Innate and Adaptive Immunity

CONFERENCE 2005-02-01 00:00:00-2005-02-07 00:00:00 Fairmont Hotel Vancouver, Vancouver, British Columbia, Canada 01 &#x2013 07 February 2005 The decision to activate an immune response is made by unique antigen presenting cells, called dendritic cells that are resting until they encounter foreign micr

Frontiers of NMR in Molecular Biology IX (A8)

CONFERENCE 2005-01-29 00:00:00-2005-02-04 00:00:00 Banff Centre, Banff, Alberta, Canada 29 January &#x2013 04 February 2005 Nuclear Magnetic Resonance (NMR) has a long history of evolving to meet new challenges of molecular biology; this evolution will be even more rapid in a genomic and post-genomic

PSEN1 M146I (G> C)

MUTATIONS PSEN1 73640373 GRCh37/hg19 rs63750391 G C g.25641G> C g.42195G> C Exon 5 Point, Missense Coding Increased Aβ42/Aβ40 and Aβ42/Aβ38; unchanged Aβ38/Aβ40 and Aβ43/Aβ40 in iPSC-derived neurons. Altered protein stability. Also, disrupted lysosome functio

PSEN1 M146I (G> A)

MUTATIONS PSEN1 73640373 GRCh37/hg19 rs63750391 G A g.25641G> A g.42195G> A Exon 5 Point, Missense Coding Increased Aβ42/Aβ40 and Aβ42/Aβ38; unchanged Aβ38/Aβ40 and Aβ43/Aβ40 in iPSC-derived neurons. Altered protein stability. Also, disrupted lysosome functio

PSEN1 M146L (A> T)

MUTATIONS PSEN1 73640371 GRCh37/hg19 rs63750306 A T g.25639A> T g.42193A> T Exon 5 Point, Missense Coding Increased Aβ42, Aβ42/Aβ total, Aβ42/Aβ40 in cells and in vitro assays and decreased Aβ37/Aβ42. Impaired calcium dynamics, mitochondrial permeability, exp

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