COMMENT Primary results from the Phase 3 study of LMTX were not significant, but a significant treatment effect was reported in a subgroup of approximately 15 percent of ACTIVE patients who were not taking concomitant ACHEI therapy. Unfortunately, the analysis ...
CONFERENCE COVERAGE SERIES In First Phase 3 Trial, the Tau Drug LMTM Did Not Work. Period. Held July 24 to 28 in Toronto, the Alzheimer’s Association International Conference showcased a field in transformation. At the clinical level, groups from Europe, North America, and Japan ...
CONFERENCE COVERAGE 2016-07-29 Conference Coverage Results of the eagerly awaited Phase 3 clinical trial of LMTM, a derivative of the dye methylene blue, generated consternation at the Alzheimer’s Association International Conference 2016, held July 22-28 in Toronto. Speaking to a ...
C2N DiagnosticsSaint Louis, United States
RESEARCH NEWS 2016-07-29 Research News Tau proteins come in two varieties in the brain, depending on how neurons splice the mRNA. The four-repeat (4R) form underlies several tauopathies, including frontotemporal dementia, but researchers have struggled to directly compare its ...
PAPER Adams SJ, DeTure MA, McBride M, Dickson DW, Petrucelli L20520830
PAPER Voit T, Topaloglu H, Straub V, Muntoni F, Deconinck N, Campion G, De Kimpe SJ, Eagle M, Guglieri M, Hood S, Liefaard L, Lourbakos A, Morgan A, Nakielny J, Quarcoo N, Ricotti V, Rolfe K, Servais L, Wardell C, Wilson R, Wright P, Kraus JE
Safety and efficacy of drisapersen for the treatment of Duchenne muscular dystrophy (DEMAND II): an exploratory, randomised, placebo-controlled phase 2 study.Lancet Neurol. 2014 Oct;13(10):987-96. Epub 2014 Sep 7 PubMed: 25209738
Banking (32 yrs); U.S. Army (25 yrs, active & reserves)Bryan, United States
Universidad Complutense de MadridMadrid, Spain
University of BarcelonaSpain
PAPER Tsai JC, Chen CW, Chu H, Yang HL, Chung MH, Liao YM, Chou KR
Comparing the Sensitivity, Specificity, and Predictive Values of the Montreal Cognitive Assessment and Mini-Mental State Examination When Screening People for Mild Cognitive Impairment and Dementia in Chinese Population.Arch Psychiatr Nurs. 2016 Aug;30(4):486-91. Epub 2016 Jan 21 PubMed: 27455923
PAPER Wei Z, Chen XC, Song Y, Pan XD, Dai XM, Zhang J, Cui XL, Wu XL, Zhu YG
Amyloid β Protein Aggravates Neuronal Senescence and Cognitive Deficits in 5XFAD Mouse Model of Alzheimer's Disease.Chin Med J (Engl). 2016 5th Aug;129(15):1835-1844. PubMed: 27453234
PAPER Dai Y, Ma T, Ren X, Wei J, Fu W, Ma Y, Xu S, Zhang Z
Tongluo Xingnao Effervescent Tablet Preserves Mitochondrial Energy Metabolism and Attenuates Cognition Deficits in APPswe/PS1De9 Mice.Neurosci Lett. 2016 Jul 23; PubMed: 27461792
PAPER Bisogno T, Oddi S, Piccoli A, Fazio D, Maccarrone M27450295
No filters selected