Gary Reiswig on Research Brief: Auguste D.'s Mutation Identified?

COMMENT In The Thousand Mile Stare, I describe a frightening scene in which my sister threatened to kill my brother-in-law because she thought he was a stranger who broke into the house. This is only one of a number of incidents in which paranoid behavior has bee

Gary Reiswig

United States

PAPER Graeber MB, Kösel S, Grasbon-Frodl E, Möller HJ, Mehraein P

Histopathology and APOE genotype of the first Alzheimer disease patient, Auguste D.

Neurogenetics. 1998 Mar;1(3):223-8. PubMed: 10737127

PAPER Graeber MB, Kösel S, Egensperger R, Banati RB, Müller U, Bise K, Hoff P, Möller HJ, Fujisawa K, Mehraein P

Rediscovery of the case described by Alois Alzheimer in 1911: historical, histological and molecular genetic analysis.

Neurogenetics. 1997 May;1(1):73-80. PubMed: 10735278

PAPER Bird TD, Lampe TH, Nemens EJ, Miner GW, Sumi SM, Schellenberg GD

Familial Alzheimer's disease in American descendants of the Volga Germans: probable genetic founder effect.

Ann Neurol. 1988 Jan;23(1):25-31. PubMed: 3345066

Kenneth Kosik on NIH Calls for More (and Different) Research on Preventive Measures

COMMENT The NIH State-of-the-Science Conference has set a threshold of evidence required to make recommendations that goes beyond what would best serve the interests of public health. This may seem paradoxical, because as scientists we demand the highest standard

Andrew Malinow

United States

Marshal Folstein

Tufts, Johns Hopkins
Miami Beach, United States

PAPER Jose A, Krishnan LK

Effect of matrix composition on differentiation of nestin-positive neural progenitors from circulation into neurons.

J Neural Eng. 2010 Jun;7(3):036009. PubMed: 20479522

Research Brief: Auguste D.'s Mutation Identified?

RESEARCH NEWS 2010-05-20 Research News Writing the latest pages of an anthropological mystery, scientists propose in this month’s Archives of Neurology that it is highly possible that Auguste Deter, the first identified Alzheimer disease patient, carried the N141I presenilin-2 mu

PAPER Chang LK, Zhao JH, Liu HL, Wu JW, Chuang CK, Liu KT, Chen JT, Tsai WB, Ho Y

The importance of steric zipper on the aggregation of the MVGGVV peptide derived from the amyloid beta peptide.

J Biomol Struct Dyn. 2010 Aug;28(1):39-50. PubMed: 20476794

PAPER

Biomarkers may help predict risk of Alzheimer's disease.

J Inherit Metab Dis. 2010 Jun 8; PubMed: 20477523

PAPER Ereshefsky L, Jhee S, Yen M, Moran S, Pretorius S, Adams J

Cerebrospinal fluid beta-amyloid and dynabridging in Alzheimer's disease drug development.

Biomark Med. 2009 Dec;3(6):711-21. PubMed: 20477709

PAPER Mattsson N, Zetterberg H

Alzheimer's disease and CSF biomarkers: key challenges for broad clinical applications.

Biomark Med. 2009 Dec;3(6):735-7. PubMed: 20477711

PAPER Juréus A, Swahn BM, Sandell J, Jeppsson F, Johnson AE, Johnström P, Neelissen JA, Sunnemark D, Farde L, Svensson SP

Characterization of AZD4694, a novel fluorinated Abeta plaque neuroimaging PET radioligand.

J Neurochem. 2010 Aug;114(3):784-94. PubMed: 20477945