ANTIBODY polyclonal manufacturer Cat# LS-C42820<br />manufacturer: LifeSpan Biosciences immunogen = synthetic peptide corresp. to aa737-751of human APP (C-terminal) recognizes both intact APP, and also the C99 fragment generated by Beta-secretase. The seq. r
ANTIBODY polyclonal manufacturer Cat# LS-C42821<br />manufacturer: LifeSpan Biosciences immunogen = synthetic peptide corresp. to aa653-662 of human APP or 1-10 of the β-amyloid peptide (N-terminal) recognizes both intact APP and the 4kD β-amyloid peptide th
ANTIBODY polyclonal manufacturer Cat# LS-C3639<br />manufacturer: LifeSpan Biosciences immunogen = synthetic peptide derived from the extreme C-terminus of human amyloid A4 protein precursor AβPP IgG APP, APLP, AICD Autogen Bioclear Rabbit Human Mouse Rat A&
ANTIBODY polyclonal manufacturer Cat# 16625<br />Reference: <br /><a href="/papers/distinct-region-specific-alpha-synuclein-oligomers-a53t-transgenic-mice-implications" target="_new">Tsika, 2010</a> lyophilized stains NS
PAPER Busquet P, Hetzenauer A, Sinnegger-Brauns MJ, Striessnig J, Singewald N
Learn Mem. 2008 May;15(5):378-86. PubMed: 18441296
ANTIBODY monoclonal 6D7 manufacturer Cat# 657010<br />Reference: <br /><a href="/papers/distinct-region-specific-alpha-synuclein-oligomers-a53t-transgenic-mice-implications" target="_new">Tsika, 2010</a> immunogen = tyro
PAPER Striessnig J, Koschak A, Sinnegger-Brauns MJ, Hetzenauer A, Nguyen NK, Busquet P, Pelster G, Singewald N
Biochem Soc Trans. 2006 Nov;34(Pt 5):903-9. PubMed: 17052224
PAPER Langwieser N, Christel CJ, Kleppisch T, Hofmann F, Wotjak CT, Moosmang S
J Neurosci. 2010 Jun 23;30(25):8367-75. PubMed: 20573883
PAPER Chodosh J, Mittman BS, Connor KI, Vassar SD, Lee ML, DeMonte RW, Ganiats TG, Heikoff LE, Rubenstein LZ, Della Penna RD, Vickrey BG
J Am Geriatr Soc. 2007 Aug;55(8):1260-8. PubMed: 17661967
madras universitychennai, India
CONFERENCE COVERAGE 2010-06-25 Conference Coverage One of the best-studied epigenetic modifications, methylation is the addition of a methyl group to a cytosine residue of DNA, usually at a cytosine paired to a guanine (CpG site). Methylation of gene promoters usually silences gene exp
RESEARCH NEWS 2010-06-25 Research News Voltage-gated calcium channels swing open with passing action potentials, allowing calcium ions into the cell, and slide shut when the membrane depolarization has passed. Two papers this month suggest that these channels—particularly the lon
RESEARCH NEWS 2010-06-25 Research News For conditions as complex and devastating as Alzheimer disease, one might assume that guideline-based care delivered by multidisciplinary experts with skilled caregiver help would make some difference for patients. However, a study published
RESEARCH NEWS 2010-06-25 Research News William of Occam contended that the simplest explanation is usually the best. Occam’s razor, as the maxim is now known, may not cut it every time, but as applied to γ-secretase—the proteolytic complex that slices and dices amyloid precursor
PAPER Li H, Monien BH, Lomakin A, Zemel R, Fradinger EA, Tan M, Spring SM, Urbanc B, Xie CW, Benedek GB, Bitan G
Biochemistry. 2010 Aug 3;49(30):6358-64. PubMed: 20568734