PAPER Misra P, Kodali R, Chemuru S, Kar K, Wetzel R27546208
Einar Sigurdsson, Ayodeji Asuni on Antibody-Mediated Targeting of Tau In Vivo Does Not Require Effector Function and Microglial Engagement.
COMMENT We read this paper with interest. Because the authors reference our work critically, we would like to clarify the points raised by the authors, specifically neuronal uptake of tau antibodies and the presence of Fc receptors on neurons. We do not dispute ...
PAPER van der Kleij H, Charles N, Karimi K, Mao YK, Foster J, Janssen L, Chang Yang P, Kunze W, Rivera J, Bienenstock J20132972
PAPER Suemitsu S, Watanabe M, Yokobayashi E, Usui S, Ishikawa T, Matsumoto Y, Yamada N, Okamoto M, Kuroda S
Fcgamma receptors contribute to pyramidal cell death in the mouse hippocampus following local kainic acid injection.Neuroscience. 2010 Mar 31;166(3):819-31. Epub 2010 Jan 13 PubMed: 20074624
PAPER Qu L, Zhang P, LaMotte RH, Ma C
Neuronal Fc-gamma receptor I mediated excitatory effects of IgG immune complex on rat dorsal root ganglion neurons.Brain Behav Immun. 2011 Oct;25(7):1399-407. Epub 2011 Apr 18 PubMed: 21521651
PAPER Mohamed HA, Mosier DR, Zou LL, Siklós L, Alexianu ME, Engelhardt JI, Beers DR, Le WD, Appel SH
Immunoglobulin Fc gamma receptor promotes immunoglobulin uptake, immunoglobulin-mediated calcium increase, and neurotransmitter release in motor neurons.J Neurosci Res. 2002 Jul 1;69(1):110-6. PubMed: 12111822
PAPER Andoh T, Kuraishi Y15486476
PAPER Andoh T, Kuraishi Y14630707
National University of SingaporeSingapore
Big Data to Knowledge (BD2K) Enhancing the Efficiency and Effectiveness of Digital Curation for Biomedical Big Data (U01)
GRANT Friday, August 26, 2016- 17:00 National Institutes of Health NIH intends to fund an estimate of seven to 10 awards, corresponding to a total of $4 million, for fiscal year 2017. December 15, 2016), by 5 p.m. local time of applicant organization. All types ...
BRAIN Initiative: Non-Invasive Neuromodulation- New Tools and Techniques for Spatiotemporal Precision (R01)
GRANT Friday, August 26, 2016- 17:00 National Institutes of Health Issuing IC and partner components intend to commit an estimated total of $3 million to fund approximately five awards. November 23, 2016, by 5 p.m. local time of applicant organization. All ...
BRAIN Initiative: Non-Invasive Neuromodulation- Mechanisms and Dose/Response Relationships for Targeted CNS Effects (R01)
GRANT Friday, August 26, 2016- 17:00 National Institutes of Health Issuing IC and partner components intend to commit an estimated total of $ 2.3 million to fund approximately four awards. November 23, 2016, by 5 p.m. local time of applicant organization. All ...
GRANT Friday, August 26, 2016- 17:00 National Institute of Neurological Disorders and Stroke The NINDS intends to commit up to $1,500,000 in FY2017 to fund one award. An award is contingent upon NIH appropriations and the submission of meritorious applications. ...
COMMENT In Jack et al., the authors propose a broad new biomarker-based disease classification scheme that could be useful in AD and other dementing disorders. This is an important paper, where the authors encourage the whole community to step back and re-examine ...
COMMENT Preclinical AD starts more than two decades before the disease onset. This indicates that asymptomatic patients may keep taking medication for many years, almost until the end of life. The medication therefore must be safe for a long time, and I would say ...
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