PAPER Medeiros R, Kitazawa M, Passos GF, Baglietto-Vargas D, Cheng D, Cribbs DH, Laferla FM
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PAPER Spencer NG, Bridges LR, Elderfield K, Amir K, Austen B, Howe FA
Quantitative evaluation of MRI and histological characteristics of the 5xFAD Alzheimer mouse brain.
Neuroimage. 2013 Aug 1;76:108-15. PubMed: 23507393PAPER
Alzheimer disease: Peripheral clearance of amyloid-β does not reduce brain levels of this peptide.
J Clin Psychiatry. 2013 Mar;74(3):e06. PubMed: 23507843PAPER Groussard M, Mauger C, Platel H
Musical long-term memory throughout the progression of Alzheimer disease.
Geriatr Psychol Neuropsychiatr Vieil. 2013 Mar 1;11(1):99-109. PubMed: 23508326Dimitrije Krstic on Neuroinflammation—A Prelude to Alzheimer's?
COMMENT If you are interested in seeing/hearing more on the inflammation-axonopathy model of AD by Irene and me, see this European Journal of Neuroscience interview. Any feedback, comments, and/or criticism are highly appreciated. krstic 0
Vicki Thompson
La Selva Beach, United States
APP
ALZPEDIA The amyloid precursor protein (APP) is central to the study of Alzheimer’s disease. Abundant in neurons, APP is a type I transmembrane protein whose proteolysis gives rise to amyloid-β (Aβ) peptides. Rare mutations in APP cause familial Alzheimer’s diseas
Can Dousing PyroGlu-Aβ Treat Alzheimer’s Disease?
CONFERENCE COVERAGE 2013-03-20 Conference Coverage Read a PDF of the entire series. Pyroglutamate Aβ is a particularly toxic version of the peptide at the center of Alzheimer’s disease pathogenesis; in fact, some scientists claim it seeds the formation of plaques (for a review, see Gun
How Cognitive Stimulation Might Protect Against Aβ Oligomers
WEBINAR 2013-03-20 Cognitive stimulation has been shown to lower the risk of Alzheimer’s disease, but what actually happens in the brain to confer protection? In the March 6 Neuron, researchers led by Dennis Selkoe report that β2-adrenergic signaling plays a key role. Wild-
PAPER Ross OA
A prognostic view on the application of individualized genomics in Parkinson's disease.
Curr Genet Med Rep. 2013 Mar;1(1):52-57. PubMed: 23504498PAPER Xiong N, Xiong J, Jia M, Liu L, Zhang X, Chen Z, Huang J, Zhang Z, Hou L, Luo Z, Ghoorah D, Lin Z, Wang T
The role of autophagy in Parkinson's disease: rotenone-based modeling.
Behav Brain Funct. 2013;9(1):13. PubMed: 23497442PAPER ILL-Raga G, Köhler C, Radiske A, Lima RH, Rosen MD, Muñoz FJ, Cammarota M
Consolidation of object recognition memory requires HRI kinase-dependent phosphorylation of eIF2α in the hippocampus.
Hippocampus. 2013 Jun;23(6):431-6. Epub 2013 Mar 18 PubMed: 23418065PAPER Li J, Huang KX, Le WD
Establishing a novel C. elegans model to investigate the role of autophagy in amyotrophic lateral sclerosis.
Acta Pharmacol Sin. 2013 May;34(5):644-50. PubMed: 23503474PAPER Martinez-Vicente M, Vila M
Alpha-synuclein and protein degradation pathways in Parkinson's disease: A pathological feed-back loop.
Exp Neurol. 2013 Mar 13; PubMed: 23499831PAPER Moriarty GM, Janowska MK, Kang L, Baum J
Exploring the accessible conformations of N-terminal acetylated α-synuclein.
FEBS Lett. 2013 Apr 17;587(8):1128-38. PubMed: 23499431Current Filters
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