CONFERENCE 2013-11-07 00:00:00-2013-11-08 00:00:00 Sheraton San Diego Hotel and Marina, San Diego, CA, U.S.A. 07 – 08 November 2013 There is increasing evidence that neurodegenerative diseases have at their basis dysfunctions in the receptors and ion channels subserving synaptic communication. T
CONFERENCE 2013-12-09 00:00:00-2013-12-09 00:00:00 The New York Academy of Sciences, New York, NY, U.S.A. 09 December 2013 Alzheimer's disease is a public health crisis that will grow to devastating proportions over the next several decades unless effective therapies are found. Two hallmark pathologi
CONFERENCE 2013-11-06 00:00:00-2013-11-08 00:00:00 Bahia Resort Hotel, San Diego, CA, U.S.A. 06 – 08 November 2013 Society for Neuroscience Satellite Event The Alzheimer’s disease (AD) research field produces a dizzying amount of publications each year. For graduate students and postdocs who ent
CONFERENCE 2013-09-09 00:00:00-2013-09-10 00:00:00 Boston, MA, U.S.A. 09 – 10 September 2013 Over the past years, this partnering and business development conference has given global biotechnology and pharmaceutical companies an opportunity to network with high-level executives from top pharma a
CONFERENCE 2013-09-09 00:00:00-2013-09-10 00:00:00 Jersey City, NJ, U.S.A. 09 – 10 September 2013 This annual Alzheimer's Drug Discovery Foundation (ADDF) conference brings together academic and industry scientists intent on accelerating the development of innovative treatments for Alzheime
RESEARCH MODELS Summary These transgenic mice express a chimeric mouse/human APP carrying the Swedish mutation under the control of the mouse prion protein promoter. This line, E1-2, was generated in parallel with line C3-3 which also expresses APP with the Swedish mutat
RESEARCH MODELS Summary These mice express human APP with the Swedish (K670N/M671L) and London (V717I) mutations. Founder animals (line J1.96) carry a single copy of the transgene. Hemizygous animals are viable and fertile and express mutant human APP mRNA at levels comp
RESEARCH MODELS Summary These double transgenic mice were created by breeding mice that express mutant APP (line C3-3) with mice that express mutant PSEN1 (line S-9). Line C3-3 mice express a chimeric mouse/human APP (isoform 695) which is driven by the mouse prion promo
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CONFERENCE COVERAGE 2013-08-18 Conference Coverage This is part 1 of a two-part series. See Part 2. Proposed research criteria for AD employ biomarkers to identify several stages of preclinical disease, and since their publication in 2011 the field has been pushing hard to test how wel
CONFERENCE COVERAGE 2013-08-18 Conference Coverage This is part 2 of a two-part series. See Part 1 Since the advent of brain amyloid imaging, researchers have been surprised to find that a substantial minority of people clinically diagnosed with Alzheimer’s disease have no detectable a
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Amyotroph Lateral Scler Frontotemporal Degener. 2013 Aug 14; PubMed: 23944734
PAPER Benarroch EE
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