PAPER Benedictus MR, Goos JD, Binnewijzend MA, Muller M, Barkhof F, Scheltens P, Prins ND, van der Flier WM

Specific risk factors for microbleeds and white matter hyperintensities in Alzheimer's disease.

Neurobiol Aging. 2013 Nov;34(11):2488-94. PubMed: 23731952

PAPER Xie Z, McAuliffe S, Swain CA, Ward SA, Crosby CA, Zheng H, Sherman J, Dong Y, Zhang Y, Sunder N, Burke D, Washicosky KJ, Tanzi RE, Marcantonio ER

Cerebrospinal Fluid Aβ to Tau Ratio and Postoperative Cognitive Change.

Ann Surg. 2013 Aug;258(2):364-369. PubMed: 23732272

PAPER Choi J, Myung W, Chung JW, Kang HS, Na DL, Kim SY, Lee JH, Han SH, Choi SH, Kim S, Carroll BJ, Kim DK

Association between functional impairment, depression, and extrapyramidal signs in neuroleptic-free patients with Alzheimer disease.

J Geriatr Psychiatry Neurol. 2013 Sep;26(3):144-50. PubMed: 23733855

Bob Finn

MS Discovery Forum
Pleasant Hill, United States

Gina Greer

United States

MAPT G303V

MUTATIONS MAPT 44087761 GRCh37/hg19 rs63751391 G T g.123796G> T g.120975G> T Exon 10 Point, Missense Coding Unknown.   Mild frontal and temporal atrophy with neuronal loss, gliosis, enlarged lateral ventricles, and microvacuolation. Accumulated tau in neurons

PAPER

Abstracts of the Sixteenth Meeting of the European Neurological Society. May 27-31, 2006. Lausanne, Switzerland.

J Neurol. 2006 May;253 Suppl 2:II3-159. PubMed: 16710641

PAPER Kodama K, Okada S, Iseki E, Kowalska A, Tabira T, Hosoi N, Yamanouchi N, Noda S, Komatsu N, Nakazato M, Kumakiri C, Yazaki M, Sato T

Familial frontotemporal dementia with a P301L tau mutation in Japan.

J Neurol Sci. 2000 May 1;176(1):57-64. PubMed: 10865093

MAPT P301L

MUTATIONS MAPT 44087755 GRCh37/hg19 rs63751273 C T g.123790C> T g.120969C> T Exon 10 Point, Missense Coding Strongly promotes β-sheet formation and accelerates the formation of paired helical filament; Does not affect exon 10 splicing. Tau aggregates consisti

David Stoller

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New Hope, United States

PAPER Bugiani O

FTDP-17: phenotypical heterogeneity within P301S.

Ann Neurol. 2000 Jul;48(1):126. PubMed: 10894228

MAPT P301S

MUTATIONS MAPT 44087754 GRCh37/hg19 rs63751438 C T Exon 10 Point, Missense Coding Recombinant tau protein with the P301S mutation showed a greatly impaired ability to promote microtubule assembly. Frontotemporal atrophy and extensive inclusions of hyperphosphorylat

PAPER Ramsey CP, Tansey MG

A survey from 2012 of evidence for the role of neuroinflammation in neurotoxin animal models of Parkinson's disease and potential molecular targets.

Exp Neurol. 2013 May 28; PubMed: 23726958

PAPER Kuruvilla KP, Nandhu MS, Paul J, Paulose CS

Oxidative stress mediated neuronal damage in the corpus striatum of 6-hydroxydopamine lesioned Parkinson's rats: neuroprotection by serotonin, GABA and bone marrow cells supplementation.

J Neurol Sci. 2013 Aug 15;331(1-2):31-7. PubMed: 23726276

PAPER Zhou L, Miranda-Saksena M, Saksena NK

Viruses and neurodegeneration.

Virol J. 2013 May 31;10:172. PubMed: 23724961