Joyce Suhy

Synarc, Inc
San Francisco, United States

Amy Duffield

Cary, United States

susuan bennet

LA, United States

PAPER Marteyn A, Maury Y, Gauthier MM, Lecuyer C, Vernet R, Denis JA, Pietu G, Peschanski M, Martinat C

Mutant human embryonic stem cells reveal neurite and synapse formation defects in type 1 myotonic dystrophy.

Cell Stem Cell. 2011 Apr 8;8(4):434-44. PubMed: 21458401

PAPER Jiang H, Mankodi A, Swanson MS, Moxley RT, Thornton CA

Myotonic dystrophy type 1 is associated with nuclear foci of mutant RNA, sequestration of muscleblind proteins and deregulated alternative splicing in neurons.

Hum Mol Genet. 2004 Dec 15;13(24):3079-88. PubMed: 15496431

PAPER Krishnan AV, Kiernan MC

Axonal function and activity-dependent excitability changes in myotonic dystrophy.

Muscle Nerve. 2006 May;33(5):627-36. PubMed: 16453325

PAPER de León MB, Cisneros B

Myotonic dystrophy 1 in the nervous system: from the clinic to molecular mechanisms.

J Neurosci Res. 2008 Jan;86(1):18-26. PubMed: 17549748

PAPER Aruga J, Mikoshiba K

Identification and characterization of Slitrk, a novel neuronal transmembrane protein family controlling neurite outgrowth.

Mol Cell Neurosci. 2003 Sep;24(1):117-29. PubMed: 14550773

Research Brief: Link Tightens Between Plasma Clusterin and AD

RESEARCH NEWS 2011-04-10 Research News Ten genes are now linked to Alzheimer’s disease through genomewide association studies (see ARF related news story). Genetic variations in and around these genes either protect against or predispose to the disease, though for most of them it

Stem Cells Point to New Target in Muscular Dystrophy

RESEARCH NEWS 2011-04-10 Research News The disease myotonic dystrophy is mainly known for how it wastes away its sufferers’ muscles, but it also attacks the nervous system. As described in the April 8 Cell Stem Cell, researchers in France used stem cells from human embryos diagno

PAPER Sun J, Singh V, Kajino-Sakamoto R, Aballay A

Neuronal GPCR controls innate immunity by regulating noncanonical unfolded protein response genes.

Science. 2011 May 6;332(6030):729-32. PubMed: 21474712

PAPER Chung JY, Lee SJ, Lee SH, Jung YS, Ha NC, Seol W, Park BJ

Direct interaction of α-synuclein and AKT regulates IGF-1 signaling: implication of Parkinson disease.

Neurosignals. 2011;19(2):86-96. PubMed: 21474915

PAPER Vezzani A, Maroso M, Balosso S, Sanchez MA, Bartfai T

IL-1 receptor/Toll-like receptor signaling in infection, inflammation, stress and neurodegeneration couples hyperexcitability and seizures.

Brain Behav Immun. 2011 Oct;25(7):1281-9. PubMed: 21473909

PAPER Neubert M, Ridder DA, Bargiotas P, Akira S, Schwaninger M

Acute inhibition of TAK1 protects against neuronal death in cerebral ischemia.

Cell Death Differ. 2011 Sep;18(9):1521-30. PubMed: 21475303

PAPER Liu C, Sawaya MR, Cheng PN, Zheng J, Nowick JS, Eisenberg D

Characteristics of amyloid-related oligomers revealed by crystal structures of macrocyclic β-sheet mimics.

J Am Chem Soc. 2011 May 4;133(17):6736-44. PubMed: 21473620