PAPER Iascone DM, Padidam S, Pyfer MS, Zhang X, Zhao L, Chin J
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PAPER Ridge PG, Mukherjee S, Crane PK, Kauwe JS, Alzheimer’s Disease Genetics Consortium
Alzheimer's disease: analyzing the missing heritability.
PLoS One. 2013;8(11):e79771. Epub 2013 Nov 7 PubMed: 24244562PAPER Ding F, Yao J, Rettberg JR, Chen S, Brinton RD
Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention.
PLoS One. 2013;8(11):e79977. Epub 2013 Nov 11 PubMed: 24244584PAPER Vignaud H, Bobo C, Lascu I, Sörgjerd KM, Zako T, Maeda M, Salin B, Lecomte S, Cullin C
A structure-toxicity study of Aß42 reveals a new anti-parallel aggregation pathway.
PLoS One. 2013;8(11):e80262. Epub 2013 Nov 11 PubMed: 24244667PAPER Kandimalla RJ, Prabhakar S, Wani WY, Kaushal A, Gupta N, Sharma DR, Grover VK, Bhardwaj N, Jain K, Gill KD
CSF p-Tau levels in the prediction of Alzheimer's disease.
Biol Open. 2013;2(11):1119-24. Epub 2013 Sep 4 PubMed: 24244848APP(V642I)KI
RESEARCH MODELS Modification Details Targeted knock-in of the V642I mutation into exon 17 of the mouse APP gene using homologous recombination and the Cre-loxP system. Neuropathology Increased Aβ42(43) relative to Aβ40 at 29 months, but without neuritic plaques, neurofib
Peter Annas
BracketWayne, United States
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Other The new Alzforum has launched, and we couldn’t be more excited! To prepare for this event, we took the time to anticipate a few questions you might have. Do I have to do anything differently to get to the website? No. Alzforum will still be at the same U
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Other Gabrielle Strobel, Executive Editor Gabrielle Strobel oversees Alzforum's editorial operations, including research and conference reporting, expert commentary, and webinar discussions. She initiated the AlzBiomarkers database and curates the Therapeu
Sara Shaheen
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ArcAβ
RESEARCH MODELS Modification Details These mice overexpress human APP695 with the Swedish (K670N/M671L) and Arctic (E693G) mutations. Neuropathology By six months of age, these mice develop amyloid pathology affecting both the brain parenchyma and vasculature. In the par
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