COMMENT It is encouraging that our data obtained in the presented study supports, rather than contradicts, the use of MB as a therapeutic agent for neurodegenerative diseases. In principle our results are in line with most preclinical MB studies published ...
COMMENT Previously, we found that Aβ secretion from neurons is mediated by autophagy. In addition, it has been shown previously that autophagosomes contain both Aβ and the Aβ-generating enzymes (Nilsson et al., 2013; Nilsson et al., 2015). The increased levels of ...
RESEARCH NEWS 2015-05-22 Research News It is well known that damaged axons from the central nervous system of mammals cannot regrow. Except perhaps they can, with the right genotype. In the May 21 Neuron online, researchers from Boston Children’s Hospital report that a mouse line ...
RESEARCH NEWS 2015-05-22 Research News Different types of motor neuron vary in their sensitivity to neurodegeneration in amyotrophic lateral sclerosis, with the neurons innervating the lateral motor column among the most susceptible. What sets them apart from less sensitive ...
PAPER Kuhn J, Hardenacke K, Shubina E, Lenartz D, Visser-Vandewalle V, Zilles K, Sturm V, Freund HJ25991080
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PAPER Jacquet L, Neueder A, Földes G, Karagiannis P, Hobbs C, Jolinon N, Mioulane M, Sakai T, Harding SE, Ilic D
Three Huntington's Disease Specific Mutation-Carrying Human Embryonic Stem Cell Lines Have Stable Number of CAG Repeats upon In Vitro Differentiation into Cardiomyocytes.PLoS One. 2015;10(5):e0126860. Epub 2015 May 20 PubMed: 25993131
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