Paris: Renamed ARIA, Vasogenic Edema Common to Anti-Amyloid Therapy

CONFERENCE COVERAGE 2011-07-29 Conference Coverage After disappointing trial results for Alzheimer’s disease (AD) drugs, all eyes are on the Phase 3 clinical trials of two monoclonal antibodies to amyloid-β: bapineuzumab, developed by Janssen Alzheimer Immunotherapy and Pfizer, and sol

PAPER Larson EB

Brains and aging: Comment on "Physical activity and cognition in women with vascular conditions" and "Activity energy expenditure and incident cognitive impairment in older adults".

Arch Intern Med. 2011 Jul 25;171(14):1258-9. PubMed: 21771895

PAPER Vercambre MN, Grodstein F, Manson JE, Stampfer MJ, Kang JH

Physical activity and cognition in women with vascular conditions.

Arch Intern Med. 2011 Jul 25;171(14):1244-50. PubMed: 21771894

PAPER Middleton LE, Manini TM, Simonsick EM, Harris TB, Barnes DE, Tylavsky F, Brach JS, Everhart JE, Yaffe K

Activity energy expenditure and incident cognitive impairment in older adults.

Arch Intern Med. 2011 Jul 25;171(14):1251-7. PubMed: 21771893

Alzheimer's Association International Conference on Alzheimer's Disease 2011

CONFERENCE COVERAGE SERIES Paris: Renamed ARIA, Vasogenic Edema Common to Anti-Amyloid Therapy Paris: Semagacestat Autopsy and Other News of Trial Tribulations Paris: More Trial News, Mixed at Best Paris: President and All, French Science Takes the Stage Paris: Beyond Genomics, Fre

Romina Gentier

Belgium

PAPER Wagner TO, Adams TE, Nett TM

GNRH interaction with anterior pituitary. I. Determination of the affinity and number of receptors for GNRH in ovine anterior pituitary.

Biol Reprod. 1979 Mar;20(2):140-9. PubMed: 222362

Fluorescence—Not Just for Protein Anymore, Now RNA, Too

RESEARCH NEWS 2011-07-29 Research News Move over, green and related fluorescent proteins. As reported in today’s issue of Science, at least one lab bench is aglow with fluorescent RNAs. Researchers led by Samie Jaffrey at Cornell University, Ithaca, New York, developed a range of

PAPER Abbruzzese G, Cossu G, Balocco M, Marchese R, Murgia D, Melis M, Galanello R, Barella S, Matta G, Ruffinengo U, Bonuccelli U, Forni GL

A pilot trial of deferiprone for neurodegeneration with brain iron accumulation.

Haematologica. 2011 Nov;96(11):1708-11. PubMed: 21791473

PAPER Parent AS, Naveau E, Gerard A, Bourguignon JP, Westbrook GL

Early developmental actions of endocrine disruptors on the hypothalamus, hippocampus, and cerebral cortex.

J Toxicol Environ Health B Crit Rev. 2011;14(5-7):328-45. PubMed: 21790315

PAPER Koch JC, Barski E, Lingor P, Bähr M, Michel U

Plasmids containing NRSE/RE1 sites enhance neurite outgrowth of retinal ganglion cells via sequestration of REST independent of NRSE dsRNA expression.

FEBS J. 2011 Sep;278(18):3472-83. PubMed: 21790997

PAPER Koszegi Z, Szego ÉM, Cheong RY, Tolod-Kemp E, Ábrahám IM

Postlesion estradiol treatment increases cortical cholinergic innervations via estrogen receptor-α dependent nonclassical estrogen signaling in vivo.

Endocrinology. 2011 Sep;152(9):3471-82. PubMed: 21791565

PAPER Kim SC, Chung JY, Im W, Kim M

Calpain cleaved-55kDa N-terminal huntingtin delocalizes from neurons to astrocytes after ischemic injury.

Cell Mol Biol (Noisy-le-grand). 2011;57 Suppl:OL1534-42. PubMed: 21791172

PAPER Haile WB, Wu J, Echeverry R, Wu F, An J, Yepes M

Tissue-type plasminogen activator has a neuroprotective effect in the ischemic brain mediated by neuronal TNF-α.

J Cereb Blood Flow Metab. 2012 Jan;32(1):57-69. PubMed: 21792242

PAPER Tweedie D, Frankola KA, Luo W, Li Y, Greig NH

Thalidomide Analogues Suppress Lipopolysaccharide-Induced Synthesis of TNF-α and Nitrite, an Intermediate of Nitric Oxide, in a Cellular Model of Inflammation.

Open Biochem J. 2011;5:37-44. PubMed: 21792375