PAPER Xu G, Fewell C, Taylor C, Deng N, Hedges D, Wang X, Zhang K, Lacey M, Zhang H, Yin Q, Cameron J, Lin Z, Zhu D, Flemington EK
SEARCH RESULTS
331009 RESULTS
PAPER Vigorito E, Perks KL, Abreu-Goodger C, Bunting S, Xiang Z, Kohlhaas S, Das PP, Miska EA, Rodriguez A, Bradley A, Smith KG, Rada C, Enright AJ, Toellner KM, Maclennan IC, Turner M
microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells.
Immunity. 2007 Dec;27(6):847-59. PubMed: 18055230PAPER Zhang Y, Diao Z, Su L, Sun H, Li R, Cui H, Hu Y
MicroRNA-155 contributes to preeclampsia by down-regulating CYR61.
Am J Obstet Gynecol. 2010 May;202(5):466.e1-7. PubMed: 20452491PAPER Wang X, Zhao Q, Matta R, Meng X, Liu X, Liu CG, Nelin LD, Liu Y
Inducible nitric-oxide synthase expression is regulated by mitogen-activated protein kinase phosphatase-1.
J Biol Chem. 2009 Oct 2;284(40):27123-34. PubMed: 19651781PAPER Leung WH, Tarasenko T, Bolland S
Differential roles for the inositol phosphatase SHIP in the regulation of macrophages and lymphocytes.
Immunol Res. 2009;43(1-3):243-51. PubMed: 18989630PAPER O'Connell RM, Chaudhuri AA, Rao DS, Baltimore D
Inositol phosphatase SHIP1 is a primary target of miR-155.
Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):7113-8. PubMed: 19359473PAPER Abba M, Mudduluru G, Allgayer H
MicroRNAs in cancer: small molecules, big chances.
Anticancer Agents Med Chem. 2012 Sep;12(7):733-43. PubMed: 22292749PAPER Buller B, Liu X, Wang X, Zhang RL, Zhang L, Hozeska-Solgot A, Chopp M, Zhang ZG
MicroRNA-21 protects neurons from ischemic death.
FEBS J. 2010 Oct;277(20):4299-307. PubMed: 20840605PAPER Janssen HL, Reesink HW, Lawitz EJ, Zeuzem S, Rodriguez-Torres M, Patel K, van der Meer AJ, Patick AK, Chen A, Zhou Y, Persson R, King BD, Kauppinen S, Levin AA, Hodges MR
Treatment of HCV infection by targeting microRNA.
N Engl J Med. 2013 May 2;368(18):1685-94. PubMed: 23534542Swapnil Gupta
JNU, New DelhiNew Delhi, India
APP751SL/PS1 KI
RESEARCH MODELS Modification Details This animal is a cross between a PSEN1 knock-in line and an APP over-expressing line. The PS1 knock-in line was generated by introducing two point mutations in the wild-type mouse PSEN1, corresponding to the mutations M233T and L235P.
PAPER Bezprozvanny IB
Calcium signaling and neurodegeneration.
Acta Naturae. 2010 Apr;2(1):72-82. PubMed: 22649630A Conference Devoted to Better Engaging Clinical Trial Volunteers
CONFERENCE COVERAGE 2013-11-26 Conference Coverage Clinical trials, particularly for Alzheimer’s disease, often struggle to find participants fast enough and retain them until the trial is over. As more drugs move into Phase 3, this is increasingly seen as a major bottleneck in the mov
Blocking a MicroRNA Slows Motor Neuron Disease in Mice
CONFERENCE COVERAGE 2013-11-26 Conference Coverage Researchers are taking aim at amyotrophic lateral sclerosis with an antisense oligonucleotide targeted toward microRNA (miRNA), those nucleic acid snippets that each regulate hundreds of mRNAs. A single anti-miRNA therapeutic could tun
APP23
RESEARCH MODELS Summary This widely-used and extensively characterized mouse model of AD was developed by researchers at Novartis and the University of Basel. These mice have a 7-fold overexpression of mutant human APP bearing the pathgenic Swedish mutation. The original
Current Filters
No filters selected