Cogentis TherapeuticsBaltimore, United States
COMMENT I think this is very nice work. It shows that FUS nuclear localization signal mutants may act through a toxic gain of function rather than a loss of function, which is fully consistent with the idea that aberrant phase transitions are the underlying ...
Iran, Islamic Republic of
RESEARCH NEWS 2016-02-12 Research News Bexarotene has shaped up to be a jack-of-all-trades in Alzheimer’s—various reports suggest that it clears plaque by boosting ApoE expression or microglia, others that it stimulates neurogenesis or rebuilds damaged dendrites. But all these ...
RESEARCH NEWS 2016-02-12 Research News What was once just an idea now seems more certain: In developed countries, the number of new cases of dementia is on the decline. In the February 11 New England Journal of Medicine, researchers led by Sudha Seshadri at the Boston University ...
PAPER Mayeda ER, Glymour MM, Quesenberry CP, Whitmer RA
RESEARCH NEWS 2016-02-12 Research News Mutations in FUS cause amyotrophic lateral sclerosis, but do they do that by interfering with the protein’s normal actions, engendering new toxic ones, or both? According to a paper in the February 4 Nature Communications, mutated FUS ...
GRANT Friday, February 12, 2016- 11:00 The ALS Association and ALS Finding a Cure The successful team(s) with the most developed plan and the appropriate reagents will receive up to $1 million in milestone payments for phase I of the challenge. Deadline for ...
Farnham, United Kingdom
PAPER Abbott KM, Pachucki MC
Associations between social network characteristics, cognitive function, and quality of life among residents in a dementia special care unit: A pilot study.Dementia (London). 2016 Feb 9; PubMed: 26862130
PAPER Mayrhofer A, Goodman C, Smeeton N
The role of Dementia Champion in dementia care: Its aspirations, development and training needs (innovative practice).Dementia (London). 2016 Feb 9; PubMed: 26862129
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