Amy Duffield on Risk factors and preventive interventions for Alzheimer disease: state of the science.

COMMENT Given the importance of magnesium (Mg) to brain function (Slutsky et al., 2010), it would seem to make sense to make sure older people are getting enough of this critical mineral. Mg plays an important role in protein kinases. Tyrosine-specific protein ki

PAPER Seelig MS

Increased need for magnesium with the use of combined oestrogen and calcium for osteoporosis treatment.

Magnes Res. 1990 Sep;3(3):197-215. PubMed: 2132751

Sonia George

Van Andel Institute
Grand Rapids, United States

PAPER Brun A, Gustafson L

The birth and early evolution of the frontotemporal dementia (FTD) concept.

J Mol Neurosci. 2011 Nov;45(3):324-9. PubMed: 21647707

PAPER Bossù P, Salani F, Alberici A, Archetti S, Bellelli G, Galimberti D, Scarpini E, Spalletta G, Caltagirone C, Padovani A, Borroni B

Loss of function mutations in the progranulin gene are related to pro-inflammatory cytokine dysregulation in frontotemporal lobar degeneration patients.

J Neuroinflammation. 2011;8:65. PubMed: 21645364

PAPER Wang Z, Zhang Y, Zhang S, Guo Q, Tan Y, Wang X, Xiong R, Ding J, Chen S

DJ-1 can inhibit microtubule associated protein 1 B formed aggregates.

Mol Neurodegener. 2011;6:38. PubMed: 21645326

PAPER Usami Y, Hatano T, Imai S, Kubo S, Sato S, Saiki S, Fujioka Y, Ohba Y, Sato F, Funayama M, Eguchi H, Shiba K, Ariga H, Shen J, Hattori N

DJ-1 associates with synaptic membranes.

Neurobiol Dis. 2011 Sep;43(3):651-62. PubMed: 21645620

PAPER Fuentealba J, Dibarrart AJ, Fuentes-Fuentes MC, Saez-Orellana F, Quiñones K, Guzmán L, Perez C, Becerra J, Aguayo LG

Synaptic failure and adenosine triphosphate imbalance induced by amyloid-β aggregates are prevented by blueberry-enriched polyphenols extract.

J Neurosci Res. 2011 Sep;89(9):1499-508. PubMed: 21647937

PAPER Proctor EA, Ding F, Dokholyan NV

Structural and thermodynamic effects of post-translational modifications in mutant and wild type Cu, Zn superoxide dismutase.

J Mol Biol. 2011 May 6;408(3):555-67. PubMed: 21396374

PAPER Vanguilder HD, Freeman WM

The hippocampal neuroproteome with aging and cognitive decline: past progress and future directions.

Front Aging Neurosci. 2011;3:8. PubMed: 21647399

PAPER Boutahar N, Wierinckx A, Camdessanche JP, Antoine JC, Reynaud E, Lassabliere F, Lachuer J, Borg J

Differential effect of oxidative or excitotoxic stress on the transcriptional profile of amyotrophic lateral sclerosis-linked mutant SOD1 cultured neurons.

J Neurosci Res. 2011 Sep;89(9):1439-50. PubMed: 21647936

PAPER Na H, Acharjee S, Jones G, Vivithanaporn P, Noorbakhsh F, McFarlane N, Maingat F, Ballanyi K, Pardo CA, Cohen EA, Power C

Interactions between human immunodeficiency virus (HIV)-1 Vpr expression and innate immunity influence neurovirulence.

Retrovirology. 2011;8:44. PubMed: 21645334

PAPER Cabriolu R, Auer S

Amyloid fibrillation kinetics: insight from atomistic nucleation theory.

J Mol Biol. 2011 Aug 5;411(1):275-85. PubMed: 21645521

PAPER Voronkov M, Braithwaite SP, Stock JB

Phosphoprotein phosphatase 2A: a novel druggable target for Alzheimer's disease.

Future Med Chem. 2011 May;3(7):821-33. PubMed: 21644827

PAPER Boutajangout A, Ingadottir J, Davies P, Sigurdsson EM

Passive immunization targeting pathological phospho-tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain.

J Neurochem. 2011 Aug;118(4):658-67. PubMed: 21644996