Legal Aid of NorthWest TexasDallas
Novartis Institute for Biomedical ResearchCambridge, United States
JOB 2015-01-27 Employer University of Oslo, Institute of Basic Medical Sciences, Department of Molecular Medicine Contact For further information please contact: Professor Farrukh Chaudhry, firstname.lastname@example.org. For questions regarding online application, please ...
PAPER Chaudhry FA, Reimer RJ, Krizaj D, Barber D, Storm-Mathisen J, Copenhagen DR, Edwards RH
Molecular analysis of system N suggests novel physiological roles in nitrogen metabolism and synaptic transmission.Cell. 1999 Dec 23;99(7):769-80. PubMed: 10619430
PAPER Jenstad M, Quazi AZ, Zilberter M, Haglerød C, Berghuis P, Saddique N, Goiny M, Buntup D, Davanger S, S Haug FM, Barnes CA, McNaughton BL, Ottersen OP, Storm-Mathisen J, Harkany T, Chaudhry FA
System A transporter SAT2 mediates replenishment of dendritic glutamate pools controlling retrograde signaling by glutamate.Cereb Cortex. 2009 May;19(5):1092-106. Epub 2008 Oct 1 PubMed: 18832333
PAPER Nissen-Meyer LS, Popescu MC, Hamdani el, Chaudhry FA
Protein kinase C-mediated phosphorylation of a single serine residue on the rat glial glutamine transporter SN1 governs its membrane trafficking.J Neurosci. 2011 Apr 27;31(17):6565-75. PubMed: 21525297
PAPER Hamdani el, Gudbrandsen M, Bjørkmo M, Chaudhry FA
The system N transporter SN2 doubles as a transmitter precursor furnisher and a potential regulator of NMDA receptors.Glia. 2012 Nov;60(11):1671-83. Epub 2012 Jul 20 PubMed: 22821889
COMMENT This excellent article by Bart de Strooper discusses the implications of the negative Phase 3 trial of Semagacestat in mild to moderate AD that led to discontinuation of the development of this compound. He points out that the once-daily regimen studied ...
COMMENT Bart De Strooper’s essay provides a well-written analysis and refreshing views on the publicly available data on the γ-secretase inhibitor semagacestat. I could not agree more with him that γ-secretase is a fascinating enzyme and academic research needs ...
San Juan, Puerto Rico
RESEARCH NEWS 2015-01-27 Research News Could an astrocyte receptor explain some of the memory deficits of Alzheimer’s disease? So suggest scientists in the January 26 Nature Neuroscience. Researchers led by Lennart Mucke of Gladstone Institute of Neurological Disease, San ...
PAPER Orr AG, Hsiao EC, Wang MM, Ho K, Kim DH, Wang X, Guo W, Kang J, Yu G, Adame A, Devidze N, Dubal DB, Masliah E, Conklin BR, Mucke L
Other The award-winning documentary “ Alive Inside ” explores how music touches and awakens people with dementia and other disorders, reconnecting their sense of self. With contributions from neurologist and author Oliver Sacks and musician Bobby McFerrin, the ...
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