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Stem Cells Treat Epileptic Symptoms in Mice

RESEARCH NEWS 2013-05-08 Research News Using stem cells to replace inhibitory neurons in the hippocampi of adult epileptic mice reduced hyperexcitability, seizures, and behavioral deficits, according to a report in the May 5 Nature Neuroscience online. It is the first time such a

Criminal Minds: Explaining Lack of Empathy in Prison Psychopaths

RESEARCH NEWS 2013-05-08 Research News People with psychopathic tendencies—who may constitute upwards of 15 percent of prison populations—poorly activate parts of the brain responsible for empathy, according to a study in the April 24 JAMA Psychiatry online. While control subject

Gammagard™ Misses Endpoints in Phase 3 Trial

RESEARCH NEWS 2013-05-08 Research News Baxter International Inc. announced topline data yesterday that showed its intravenous immunoglobulin (IVIG) therapy, known as Gammagard™, failed to meet primary endpoints of slowing cognitive and functional decline in a Phase 3 study of 390

PAPER Ramos EM, Latourelle JC, Gillis T, Mysore JS, Squitieri F, Di Pardo A, Di Donato S, Gellera C, Hayden MR, Morrison PJ, Nance M, Ross CA, Margolis RL, Gomez-Tortosa E, Ayuso C, Suchowersky O, Trent RJ, McCusker E, Novelletto A, Frontali M, Jones R, Ashizawa T, Frank S, Saint-Hilaire MH, Hersch SM, Rosas HD, Lucente D, Harrison MB, Zanko A, Abramson RK, Marder K, Gusella JF, Lee JM, Alonso I, Sequeiros J, Myers RH, MacDonald ME

Candidate glutamatergic and dopaminergic pathway gene variants do not influence Huntington's disease motor onset.

Neurogenetics. 2013 May 4; PubMed: 23644918

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