PAPER Meli G, Lecci A, Manca A, Krako N, Albertini V, Benussi L, Ghidoni R, Cattaneo A
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PAPER Furukawa K, Kamada M, Ishiki A, Tomita N, Arai H
[Clinical diagnosis].
Nihon Rinsho. 2014 Apr;72(4):667-72. PubMed: 24796095PAPER Veronese S, Valle A, Chiò A, Calvo A, Oliver D
The last months of life of people with amyotrophic lateral sclerosis in mechanical invasive ventilation: A qualitative study.
Amyotroph Lateral Scler Frontotemporal Degener. 2014 May 27;:1-6. PubMed: 24863495PAPER Lo AC, De Maeyer JH, Vermaercke B, Callaerts-Vegh Z, Schuurkes JA, D'Hooge R
SSP-002392, a new 5-HT4 receptor agonist, dose-dependently reverses scopolamine-induced learning and memory impairments in C57Bl/6 mice.
Neuropharmacology. 2014 Oct;85:178-89. Epub 2014 May 23 PubMed: 24863046PAPER Kelly ME, Loughrey D, Lawlor BA, Robertson IH, Walsh C, Brennan S
The impact of exercise on the cognitive functioning of healthy older adults: a systematic review and meta-analysis.
Ageing Res Rev. 2014 Jul;16:12-31. Epub 2014 May 23 PubMed: 24862109PAPER Chuong NN, Trung BH, Luan TC, Hung TM, Dang NH, Dat NT
Anti-amnesic effect of alkaloid fraction from Lycopodiella cernua (L.) Pic. Serm. on scopolamine-induced memory impairment in mice.
Neurosci Lett. 2014 Jul 11;575:42-6. Epub 2014 May 23 PubMed: 24861508Andrew Wolf on PET Tracers Enlighten at Neurology Conference
COMMENT I agree with the comments from Dr. Rabinovici regarding ApoE possibly playing a multifactorial role in AD risk over the lifespan. In addition to the excellent articles by Huang and Mucke, and Jagust and Mormino, I would like to mention two reviews that I
Imme Thom on Art as Therapy—Can Creative Expression Soothe Dementia Symptoms?
COMMENT I am an art and sandplay therapist. I know that the potential of art for people who, for whatever reason, have lost the ability to express themselves clearly has not even been dreamed of. I have had success through art and sandplay, where all other method
Wataru Araki on Abundance of Aβ₅-x like immunoreactivity in transgenic 5XFAD, APP/PS1KI and 3xTG mice, sporadic and familial Alzheimer's disease.
COMMENT The article by Guzman et al. provided immunohistochemical evidence that Aβ5-x, one of the N-truncated Aβ species, is more abundantly present in the brains of familial Alzheimer’s disease (FAD) cases than sporadic AD (SAD) cases. Vascular Aβ5-x immunoreact
Albrecht Stöffler on Antidepressant Citalopram Shows Promise as Future Anti-Amyloid Agent
COMMENT If we believe both the Porsteinsson results regarding cognition and the new data on SSRIs lowering Aβ, this may—together with the results of the γ-secretase inhibitor trials—indicate that lowering Aβ production as such is not only useless but may even be
PAPER Probst C, Gethmann JM, Heuser R, Niemann H, Conraths FJ
Direct costs of bovine spongiform encephalopathy control measures in Germany.
Zoonoses Public Health. 2013 Dec;60(8):577-95. Epub 2013 Jan 10 PubMed: 23302301John Trojanowski on Distinct tau prion strains propagate in cells and mice and define different tauopathies.
COMMENT This study is an elegant demonstration of tau strains, which extends earlier work that demonstrated strains of tau using human brain lysates (Claveguera et al., 2013). Indeed, Sanders et al. add to the growing body of literature demonstrating that other n
PAPER Prusiner SB
Novel proteinaceous infectious particles cause scrapie.
Science. 1982 Apr 9;216(4542):136-44. PubMed: 6801762Marc Diamond on Like Prions, Tau Strains Are True to Form
COMMENT I agree with Mathias Jucker that the current debate about whether we should refer to protein amyloids that cause disease as “prions” or “prion-like” or some other word is not fruitful. One could theoretically use “infectious” as a critical criterion to de
PAPER Hanan E, Solomon B
Protective effect of monoclonal antibodies against Alzheimer’s beta-amyloid aggregation
Amyloid. 1996;3(2):130-3.Current Filters
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