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Antidepressant- and anxiolytic-like effects of the phosphodiesterase-4 inhibitor rolipram on behavior depend on cyclic AMP response element binding protein-mediated neurogenesis in the hippocampus.
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The phosphodiesterase inhibitor rolipram promotes survival of newborn hippocampal neurons after ischemia.
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Enhanced long-term potentiation and impaired learning in phosphodiesterase 4D-knockout (PDE4D) mice.
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Behav Brain Res. 2004 Sep 23;154(1):99-106. PubMed: 15302115Colin Dingwall on Mark Smith, 45, Is Struck and Killed by Hit-and-Run Driver
COMMENT I first met Mark when we sat together on a shuttle bus at a meeting many years ago. I was struck by his energy, enthusiasm and ability to look at problems in a novel way. We kept in touch over the years and I placed a high value on our interactions and me
Amber Dance Interviews R. Douglas Fields
INTERVIEWS 2011-01-10 Interviews R. Douglas Fields The Other Brain For R. Douglas Fields, the revelation came one day in 1994. He had witnessed the flash of calcium-sensitive dye many times as he stimulated neurons under the microscope. But for the first time that day, ensco
Wai-Tong Chien
The Chinese University of Hong KongHong Kong
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RESEARCH NEWS 2011-01-10 Research News New research in this week’s Journal of Neuroscience sustains hopes of boosting cognition through enhancement of the cyclic AMP (cAMP) signaling pathway that turns on memory genes. Using genetic and RNA interference-mediated knockdown approac
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Ethanol down regulates the expression of myelin proteolipid protein in the rat hippocampus.
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Erythropoietin is neuroprotective in a transgenic mouse model of multiple system atrophy.
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Calcium binding to PICK1 is essential for the intracellular retention of AMPA receptors underlying long-term depression.
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An engineered zinc finger protein activator of the endogenous glial cell line-derived neurotrophic factor gene provides functional neuroprotection in a rat model of Parkinson's disease.
J Neurosci. 2010 Dec 8;30(49):16469-74. PubMed: 21147986Current Filters
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