RESEARCH NEWS 2016-08-26 Research News The relationship between late-onset Alzheimer’s disease and cardiovascular problems such as hypertension, heart disease, and diabetes is complicated, to say the least. However, according to a large, longitudinal study published August 15 in ...
PAPER Anzai I, Toichi K, Tokuda E, Mukaiyama A, Akiyama S, Furukawa Y
Screening of Drugs Inhibiting In vitro Oligomerization of Cu/Zn-Superoxide Dismutase with a Mutation Causing Amyotrophic Lateral Sclerosis.Front Mol Biosci. 2016;3:40. Epub 2016 Aug 9 PubMed: 27556028
PAPER Ringer C, Tune S, Bertoune MA, Schwarzbach H, Tsujikawa K, Weihe E, Schütz B
Disruption of calcitonin gene-related peptide signaling accelerates muscle denervation and dampens cytotoxic neuroinflammation in SOD1 mutant mice.Cell Mol Life Sci. 2016 Aug 23; PubMed: 27554772
PAPER Goode A, Rea S, Sultana M, Shaw B, Searle MS, Layfield R27554286
PAPER Orrù S, Coni P, Floris A, Littera R, Carcassi C, Sogos V, Brancia C
Reduced stress granule formation and cell death in fibroblasts with the A382T mutation of TARDBP gene: evidence for loss of TDP-43 nuclear function.Hum Mol Genet. 2016 Aug 22; PubMed: 27554113
PAPER Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, Ishitani R, Kamei K, Takeyoshi I, Kawakami H, Iwai K, Hatada I, Sawasaki T, Ito H, Nureki O, Tokunaga F
Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis.Nat Commun. 2016 Aug 24;7:12547. PubMed: 27552911
PAPER Nakajima K, Mikoshiba K, Miyata T, Kudo C, Ogawa M9223338
PAPER Ogawa M, Miyata T, Nakajima K, Yagyu K, Seike M, Ikenaka K, Yamamoto H, Mikoshiba K
The reeler gene-associated antigen on Cajal-Retzius neurons is a crucial molecule for laminar organization of cortical neurons.Neuron. 1995 May;14(5):899-912. PubMed: 7748558
COMMENT A number of aspects of this recent paper have been somewhat sensationalized in various different ways. The first of these is the estimated number of papers that are truly affected, and this is something that the original authors wished to change, and they ...
COMMENT This is an important and positive study for the field of neuroimaging. Though there are some flaws in the analyses, as pointed out by the SPM folks, the important points that this study brings forward need to be examined closely. What does the study say? ...
RESEARCH NEWS 2016-08-25 Research News Task-based functional MRI has opened a window to the mind, allowing researchers to observe patterns of brain activity as people process information. In the Alzheimer’s field, the technology has helped researchers identify early functional ...
PAPER Havekes R, Park AJ, Tudor JC, Luczak VG, Hansen RT, Ferri SL, Bruinenberg VM, Poplawski SG, Day JP, Aton SJ, Radwańska K, Meerlo P, Houslay MD, Baillie GS, Abel T
Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1.Elife. 2016;5 PubMed: 27549340
PAPER Cavanagh C, Tse YC, Nguyen HB, Krantic S, Breitner JC, Quirion R, Wong TP
Inhibiting tumor necrosis factor-α before amyloidosis prevents synaptic deficits in an Alzheimer's disease model.Neurobiol Aging. 2016 Jul 25;47:41-49. PubMed: 27552480
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