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PAPER Zheng F, Lammert K, Nixdorf-Bergweiler BE, Steigerwald F, Volkmann J, Alzheimer C
Axonal failure during high frequency stimulation of rat subthalamic nucleus.
J Physiol. 2011 Jun 1;589(Pt 11):2781-93. PubMed: 21486784PAPER Darocha-Souto B, Scotton TC, Coma M, Serrano-Pozo A, Hashimoto T, Serenó L, Rodríguez M, Sánchez B, Hyman BT, Gómez-Isla T
Brain oligomeric β-amyloid but not total amyloid plaque burden correlates with neuronal loss and astrocyte inflammatory response in amyloid precursor protein/tau transgenic mice.
J Neuropathol Exp Neurol. 2011 May;70(5):360-76. PubMed: 21487307PAPER Kouri N, Whitwell JL, Josephs KA, Rademakers R, Dickson DW
Corticobasal degeneration: a pathologically distinct 4R tauopathy.
Nat Rev Neurol. 2011 May;7(5):263-72. PubMed: 21487420PAPER Gutierrez-Cuesta J, Tajes M, Jimenez A, Camins A, Pallas M
[Effects of melatonin in the brain of the senescence-accelerated mice-prone 8 (SAMP8) model].
Rev Neurol. 2011 May 16;52(10):618-22. PubMed: 21488009Amy Duffield on The Role of Insulin Resistance in Brain Aging and Dementia
COMMENT Given the following facts: There is an association between insulin resistance and Alzheimer's disease, magnesium helps regulate insulin, and intracellular Mg concentration has been shown to offset calcium-related excitation-contraction coupling.... H
Joel Ross on Clinical and neuropathological features of the arctic APP gene mutation causing early-onset Alzheimer disease.
COMMENT Could these "rings" be similar to the amyloid rings known as "Biondi rings" seen in the choroid plexus of AD patients on autopsy? 0 jrossmd Biondi ring tangles in the choroid plexus of Alzheimer's disease and normal aging brains:
PAPER Wen GY, Wisniewski HM, Kascsak RJ
Biondi ring tangles in the choroid plexus of Alzheimer's disease and normal aging brains: a quantitative study.
Brain Res. 1999 Jun 19;832(1-2):40-6. PubMed: 10375650Jim Burgess on Herpes Simplex and Alzheimer’s—Time to Think Again?
COMMENT I’m a caregiver not a medical professional. However, has anyone considered the herpes roster virus? It is a common illness, but the reoccurrence as shingles is not universal. It lies latent for decades and has slow growth—as does AD. It affects nerve cell
Mary Newport on Barcelona: Live and Learn—γ-Secretase Inhibitors Fade, Modulators Rise
COMMENT Connecting the Dots: Perhaps β Amyloid Is at the Scene of the Crime as Part of the Clean-Up Crew, Not the Culprit When the dots are connected among five seemingly unrelated research papers, a hypothesis emerges that appears to support the contention that
PAPER Rossini AA, Like AA, Chick WL, Appel MC, Cahill GF
Studies of streptozotocin-induced insulitis and diabetes.
Proc Natl Acad Sci U S A. 1977 Jun;74(6):2485-9. PubMed: 142253PAPER Tong M, Neusner A, Longato L, Lawton M, Wands JR, de la Monte SM
Nitrosamine exposure causes insulin resistance diseases: relevance to type 2 diabetes mellitus, non-alcoholic steatohepatitis, and Alzheimer's disease.
J Alzheimers Dis. 2009;17(4):827-44. PubMed: 20387270PAPER
State of aggregation.
Neuron. 1995 Jun;14(6):1105-16. PubMed: 21445061PAPER Håkansson S, Heyner S, Sundqvist KG, Bergström S
The presence of paternal H-2 antigens on hybrid mouse blastocysts during experimental delay of implantation and the disappearance of these antigens after onset of implantation.
Int J Fertil. 1975;20(3):137-40. PubMed: 4392PAPER Ablad B, Ljung B, Sannerstedt R
Haemodynamic effects of beta-adrenorecptor blockers in hypertension.
Drugs. 1976;11 SUPPL 1:127-34. PubMed: 6245Current Filters
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