PAPER Jeyakumar M, Thomas R, Elliot-Smith E, Smith DA, van der Spoel AC, d'Azzo A, Perry VH, Butters TD, Dwek RA, Platt FM

Central nervous system inflammation is a hallmark of pathogenesis in mouse models of GM1 and GM2 gangliosidosis.

Brain. 2003 Apr;126(Pt 4):974-87. PubMed: 12615653

PAPER Auer IA, Schmidt ML, Lee VM, Curry B, Suzuki K, Shin RW, Pentchev PG, Carstea ED, Trojanowski JQ

Paired helical filament tau (PHFtau) in Niemann-Pick type C disease is similar to PHFtau in Alzheimer's disease.

Acta Neuropathol. 1995;90(6):547-51. PubMed: 8615074

Back to Basics? Boosting pH Puts Cells in Progranulin-Pumping Mode

RESEARCH NEWS 2011-02-06 Research News For people with mutations in progranulin that lead to frontotemporal dementia, the problem is one of production—they have one good progranulin gene, but it cannot make enough of the protein. In the February 2 Journal of Neuroscience, scienti

A Surfeit of Sphingolipids Sours Aβ Digestion

RESEARCH NEWS 2011-02-06 Research News The ancient Sphinx posed riddles to travelers before devouring them. Sphingolipids, the Sphinx’s modern namesake, may hold clues to the riddle of why some neurons fail to digest Aβ. In this week’s Journal of Neuroscience, researchers led by

PAPER Casanova R, Espeland MA, Goveas JS, Davatzikos C, Gaussoin SA, Maldjian JA, Brunner RL, Kuller LH, Johnson KC, Mysiw WJ, Wagner B, Resnick SM,

Application of machine learning methods to describe the effects of conjugated equine estrogens therapy on region-specific brain volumes.

Magn Reson Imaging. 2011 May;29(4):546-53. PubMed: 21292420

PAPER Bell KF, Hardingham GE

The influence of synaptic activity on neuronal health.

Curr Opin Neurobiol. 2011 Apr;21(2):299-305. PubMed: 21292474

PAPER Jeong GB, Mojsilovic-Petrovic J, Boccitto M, Kalb R

Signaling events in axons and/or dendrites render motor neurons vulnerable to mutant superoxide dismutase toxicity.

J Neurosci. 2011 Jan 5;31(1):295-9. PubMed: 21209215

PAPER Gutierrez-Merino C, Lopez-Sanchez C, Lagoa R, Samhan-Arias AK, Bueno C, Garcia-Martinez V

Neuroprotective actions of flavonoids.

Curr Med Chem. 2011;18(8):1195-212. PubMed: 21291366

PAPER Danielyan L 2nd, Schäfer R, von Ameln-Mayerhofer A, Bernhard F, Verleysdonk S, Buadze M, Lourhmati A, Klopfer T, Schaumann F, Schmid B, Koehle C, Proksch B, Weissert R, Reichardt HM, van den Brandt J, Buniatian GH, Schwab M, Gleiter CH, Frey WH

Therapeutic efficacy of intranasally delivered mesenchymal stem cells in a rat model of Parkinson disease.

Rejuvenation Res. 2011 Feb;14(1):3-16. Epub 2011 Feb 3 PubMed: 21291297

PAPER Lavdas AA, Papastefanaki F, Thomaidou D, Matsas R

Cell adhesion molecules in gene and cell therapy approaches for nervous system repair.

Curr Gene Ther. 2011 Apr;11(2):90-100. PubMed: 21291359

PAPER Cui M, Huang Y, Tian C, Zhao Y, Zheng J

FOXO3a inhibits TNF-α- and IL-1β-induced astrocyte proliferation:Implication for reactive astrogliosis.

Glia. 2011 Apr;59(4):641-54. PubMed: 21294163

PAPER Chen BS, Thomas EV, Sanz-Clemente A, Roche KW

NMDA receptor-dependent regulation of dendritic spine morphology by SAP102 splice variants.

J Neurosci. 2011 Jan 5;31(1):89-96. PubMed: 21209193

PAPER Cloe AL, Orgel JP, Sachleben JR, Tycko R, Meredith SC

The Japanese mutant Aβ (ΔE22-Aβ(1-39)) forms fibrils instantaneously, with low-thioflavin T fluorescence: seeding of wild-type Aβ(1-40) into atypical fibrils by ΔE22-Aβ(1-39).

Biochemistry. 2011 Mar 29;50(12):2026-39. Epub 2011 Feb 24 PubMed: 21291268

PAPER Istrate AN, Mantsyzov AB, Kozin SA, Pol'shakov VI

[Optimization of the methods for small peptide solution structure determination by NMR spectroscopy].

Mol Biol (Mosk). 2010 Nov-Dec;44(6):1075-85. PubMed: 21290829

PAPER Zhang P, Guan SS, Jiang GH

[Effects of electroacupuncture on expression of Abeta positive cells of the hippocampus and SOD activity in rats with streptozocin-Alzheimer's disease].

Zhongguo Zhen Jiu. 2010 Dec;30(12):1007-10. PubMed: 21290839