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Elusive or Not, Aβ Oligomers Are in BioPharma Crosshairs

RESEARCH NEWS 2017-12-14 Research News They are difficult to isolate, hard to quantify, and virtually uncharacterized structurally. No matter the maddening vagueness of the target, scientists think they have therapies to go after Aβ oligomers. At this year’s Clinical Trials in ...

Blood, the Secret Sauce? Focus on Plasma Promises AD Treatment

CONFERENCE COVERAGE 2017-12-14 Conference Coverage In mice, infusing young blood rejuvenates the old, and even staves off some of the changes linked to Alzheimer’s. It’s too early to say if the same is true in people, but first results look encouraging. At the 2017 Clinical Trials on ...

PAPER Connolly NM, Theurey P, Adam-Vizi V, Bazan NG, Bernardi P, Bolaños JP, Culmsee C, Dawson VL, Deshmukh M, Duchen MR, Düssmann H, Fiskum G, Galindo MF, Hardingham GE, Hardwick JM, Jekabsons MB, Jonas EA, Jordán J, Lipton SA, Manfredi G, Mattson MP, McLaughlin B, Methner A, Murphy AN, Murphy MP, Nicholls DG, Polster BM, Pozzan T, Rizzuto R, Satrústegui J, Slack RS, Swanson RA, Swerdlow RH, Will Y, Ying Z, Joselin A, Gioran A, Moreira Pinho C, Watters O, Salvucci M, Llorente-Folch I, Park DS, Bano D, Ankarcrona M, Pizzo P, Prehn JH

Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases.

Cell Death Differ. 2017 Dec 11; PubMed: 29229998

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