203313 RESULTS

Gregor Bieri on ALS-FTD Mouse Model Develops Motor Neuron Disease

COMMENT Li et al. have developed a series of new mouse lines in which either wild-type (WT) or two ALS/FTD-associated mutated forms (P497S and P506T) of the human UBQLN2 gene are overexpressed broadly in neurons. The expression of the mutated but not the WT ...

Todd Cohen on Is Tau Phosphorylation All Bad?

COMMENT This paper is a very important step toward identifying the kinases and site-specific post-translational events that determine tau toxicity. These findings are highly suggestive that tau hyperphosphorylation is not the whole story in terms of AD ...

Todd E. Golde on Field Loses Chad Dickey, 40, to Cancer

COMMENT Chad was a great friend and colleague. I first met him when I was a young faculty member at Mayo Clinic in Florida, and Chad was a postdoctoral fellow. He was later promoted to a research track assistant professor and I soon thereafter became his chair. ...

Terrence Town on Field Loses Chad Dickey, 40, to Cancer

COMMENT What a terrible loss for Chad’s family, friends, and the scientific community. I personally feel his loss, as Chad and I were close friends for over 15 years. I have such fond memories of driving together to the AFAR conference in Santa Barbara, ...

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