RESEARCH NEWS 2015-03-28 Research News Tiny brain bleeds in Alzheimer’s patients put them at a higher risk of stroke and cardiovascular disease. Which one develops depends on where those microbleeds occur, according to the latest findings from the MISTRAL Study. Scientists led by ...
PAPER Benedictus MR, Prins ND, Goos JD, Scheltens P, Barkhof F, van der Flier WM25798556
RESEARCH NEWS 2015-03-27 Research News When individual proteins form aggregates, they shed the shapes they once took as lone monomers for others that fit in with the collective. A new technique capitalizes on this often-disorderly transition to detect different strains of ...
Emily Reedich, C.J. Heckman, Katharina Quinlan on Motor Cortex Layer V Pyramidal Neurons Exhibit Dendritic Regression, Spine Loss, and Increased Synaptic Excitation in the Presymptomatic hSOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis.
COMMENT Cortical abnormalities in hSOD1 G93A mouse model confirm a key role of synaptic dysfunction in ALS Amyotrophic lateral sclerosis (ALS) is characterized by the concomitant dysfunction of corticospinal motoneurons (CSMNs) in the primary motor cortex, and ...
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Two types of thalamocortical projections from the motor thalamic nuclei of the rat: a single neuron-tracing study using viral vectors.Cereb Cortex. 2009 Sep;19(9):2065-77. Epub 2009 Jan 27 PubMed: 19174446
PAPER Bilsland LG, Nirmalananthan N, Yip J, Greensmith L, Duchen MR18808448
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Postnatal dendritic development in lumbar motoneurons in mutant superoxide dismutase 1 mouse model of amyotrophic lateral sclerosis.Neuroscience. 2012 May 3;209:144-54. Epub 2012 Feb 11 PubMed: 22387111
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