Chris Carter on Herpes Simplex and Alzheimer’s—Time to Think Again?

COMMENT To fuel the debate, there is a database relevant to herpes simplex and Alzheimer's disease. This annotates various Alzheimer's disease susceptibility genes in relation to the viral lifecycle, and a database of herpes simplex host/viral interacti

Fernando Bartolome

Institute of Neurology
London

Kuo Song

China

A BAD Mitochondrial Dehydrogenase—A Good AD Drug Target?

RESEARCH NEWS 2011-02-14 Research News An enzyme that breaks down alcohols in mitochondria also binds Aβ, and new research suggests that disrupting this interaction protects waning mitochondria and improves spatial memory in a mouse model of Alzheimer’s disease. Mitochondria in t

Warning on Antipsychotics Heeded, But What’s the Alternative?

RESEARCH NEWS 2011-02-14 Research News Seniors with dementia received fewer antipsychotic prescriptions after the U.S. Government issued a black box warning in 2005, according to a report in this month’s Archives of General Psychiatry. The warning, which linked the medications to

Hosni Azhar

Malaysia

Pablo Martinez-Lage

Fundacion CITA.alzheimer. Center for research and advanced therapies
San Sebsatian/Donostia, Spain

PAPER Borroni B, Grassi M, Archetti S, Papetti A, Del Bo R, Bonvicini C, Comi GP, Gennarelli M, Bellelli G, Di Luca M, Padovani A

Genetic background predicts poor prognosis in frontotemporal lobar degeneration.

Neurodegener Dis. 2011;8(5):289-95. PubMed: 21311163

PAPER Zhu Y, Duan C, Lü L, Gao H, Zhao C, Yu S, Uéda K, Chan P, Yang H

α-Synuclein overexpression impairs mitochondrial function by associating with adenylate translocator.

Int J Biochem Cell Biol. 2011 May;43(5):732-41. PubMed: 21310263

PAPER Dou Chang, Shuling Wang, Jinliang Zhang, Sheng Wang

Effect of exposure to high temperatures during early pregnancy on hippocampal-dependent learning and memory integrity in neonatal rats.

Toxicol Ind Health. 2011 Jun;27(5):431-5. PubMed: 21310774

PAPER Milatovic D, Aschner M

Measurement of isoprostanes as markers of oxidative stress in neuronal tissue.

Curr Protoc Toxicol. 2009 Feb;Chapter 12:Unit12.14. PubMed: 20191108

PAPER Willeumier KC, Taylor DV, Amen DG

Elevated BMI is associated with decreased blood flow in the prefrontal cortex using SPECT imaging in healthy adults.

Obesity (Silver Spring). 2011 May;19(5):1095-7. PubMed: 21311507

PAPER Couillard-Despres S, Iglseder B, Aigner L

Neurogenesis, cellular plasticity and cognition: the impact of stem cells in the adult and aging brain--a mini-review.

Gerontology. 2011;57(6):559-64. PubMed: 21311170

PAPER Wu G, Ju L, Jin T, Chen L, Shao L, Wang Y, Liu B

Local delivery of recombinant human bone morphogenetic protein-2 increases axonal regeneration and the expression of tau protein after facial nerve injury.

J Int Med Res. 2010 Sep-Oct;38(5):1682-8. PubMed: 21309482

PAPER Wang HY, Ying YL, Li Y, Kraatz HB, Long YT

Nanopore Analysis of β-Amyloid Peptide Aggregation Transition Induced by Small Molecules.

Anal Chem. 2011 Feb 10; PubMed: 21309531