PAPER Saporta MA, Grskovic M, Dimos JT
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PAPER Klementieva O, Benseny-Cases N, Gella A, Appelhans D, Voit B, Cladera J
Dense shell glycodendrimers as potential nontoxic anti-amyloidogenic agents in Alzheimer's disease. Amyloid--dendrimer aggregates morphology and cell toxicity.
Biomacromolecules. 2011 Nov 14;12(11):3903-9. PubMed: 21936579PAPER Han M, Liu Y, Zhang B, Qiao J, Lu W, Zhu Y, Wang Y, Zhao C
Salvianic borneol ester reduces β-amyloid oligomers and prevents cytotoxicity.
Pharm Biol. 2011 Oct;49(10):1008-13. PubMed: 21936627PAPER Ready RE, Baran B, Chaudhry M, Schatz K, Gordon J, Spencer RM
Apolipoprotein E-e4, Processing Speed, and White Matter Volume in a Genetically Enriched Sample of Midlife Adults.
Am J Alzheimers Dis Other Demen. 2011 Sep;26(6):463-8. PubMed: 21937476PAPER Savonenko AV, Melnikova T, Hiatt A, Li T, Worley PF, Troncoso JC, Wong PC, Price DL
Alzheimer's therapeutics: translation of preclinical science to clinical drug development.
Neuropsychopharmacology. 2012 Jan;37(1):261-77. PubMed: 21937983PAPER Martin A, Giuliano A, Collaro D, De Vivo G, Sedia C, Serretiello E, Gentile V
Possible involvement of transglutaminase-catalyzed reactions in the physiopathology of neurodegenerative diseases.
Amino Acids. 2011 Sep 22; PubMed: 21938398PAPER Zou X, Coyle D, Wong-Lin K, Maguire L
Beta-amyloid induced changes in A-type K(+) current can alter hippocampo-septal network dynamics.
J Comput Neurosci. 2011 Sep 21; PubMed: 21938438PAPER Saavedra JM
Angiotensin II AT(1) Receptor Blockers Ameliorate Inflammatory Stress: A Beneficial Effect for the Treatment of Brain Disorders.
Cell Mol Neurobiol. 2011 Sep 22; PubMed: 21938488PAPER Ossenkoppele R, van Berckel BN, Prins ND
Amyloid imaging in prodromal Alzheimer's disease.
Alzheimers Res Ther. 2011 Sep 19;3(5):26. PubMed: 21936965PAPER Ryan JJ, McCloy C, Rundquist P, Srinivasan V, Laird R
Fall risk assessment among older adults with mild Alzheimer disease.
J Geriatr Phys Ther. 2011 Jan-Mar;34(1):19-27. PubMed: 21937888PAPER Roach KE, Tappen RM, Kirk-Sanchez N, Williams CL, Loewenstein D
A Randomized Controlled Trial of an Activity Specific Exercise Program for Individuals With Alzheimer Disease in Long-term Care Settings.
J Geriatr Phys Ther. 2011 Apr-Jun;34(2):50-6. PubMed: 21937893PAPER Santacruz KS, Sonnen JA, Pezhouh MK, Desrosiers MF, Nelson PT, Tyas SL
Alzheimer disease pathology in subjects without dementia in 2 studies of aging: the Nun Study and the Adult Changes in Thought Study.
J Neuropathol Exp Neurol. 2011 Oct;70(10):832-40. PubMed: 21937909Ammar Al-Chalabi on Corrupt Code: DNA Repeats Are Common Cause for ALS and FTD
COMMENT This is a very important finding, with implications for sporadic and familial ALS and FTD. The discovery in Rosa Rademakers' lab really hinged on following up apparently non-Mendelian inheritance of a microsatellite marker, something that many people
John Trojanowski on Corrupt Code: DNA Repeats Are Common Cause for ALS and FTD
COMMENT At long last, these two papers from the Traynor and Rademakers groups resolve the mystery of the gene on chromosome 9 implicated in ALS and FTD. The authors identify massively expanded GGGGCC repeats in the non-coding region of a gene known as C9ORF72. Un
PAPER Snell RG, MacMillan JC, Cheadle JP, Fenton I, Lazarou LP, Davies P, MacDonald ME, Gusella JF, Harper PS, Shaw DJ
Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease.
Nat Genet. 1993 Aug;4(4):393-7. PubMed: 8401588Current Filters
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